C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sodium channel, voltage-gated, type II, alpha 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000100067 Scn2a1-201 ENSMUSG00000075318 10090 + 2:65670445-65767447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000100067
Transcript ID Adipose Adrenal Bladder Brain Breast Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000100067 0.074±0.00 0.079±0.02 0.403±0.00 7.564±4.52 0.126±0.04 0.046±0.00 0.021±0.01 0.105±0.01 0.143±0.08 0.021±0.01 0.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CO CIL_0006CO_0002 CGP 2:65457118-65767447
CIL_0006CJ CIL_0006CJ_0002 CGP 2:65620857-66031546

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 TAS voltage-gated sodium channel complex
GO:0005248 IDA voltage-gated sodium channel activity
GO:0006814 IDA sodium ion transport
GO:0007399 IMP nervous system development
GO:0008627 IMP intrinsic apoptotic signaling pathway in response to osmotic stress
GO:0014704 IDA intercalated disc
GO:0016020 IDA membrane
GO:0019228 IBA neuronal action potential
GO:0030315 IDA T-tubule
GO:0030424 IDA axon
GO:0033270 IDA paranode region of axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0051402 IMP neuron apoptotic process
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000022761 scn8ab-201 protein_coding Danio_rerio 0 1777
ENSDART00000151299 scn8ab-001 protein_coding Danio_rerio 0 1777
ENSDART00000104004 scn4ab-201 protein_coding Danio_rerio 0 822
ENSDART00000044157 scn4ab-001 protein_coding Danio_rerio 0 819
ENSDART00000083256 scn12aa-201 protein_coding Danio_rerio 0 811
ENST00000283254 SCN3A-001 protein_coding Homo_sapiens 0 5001
ENST00000283256 SCN2A-001 protein_coding Homo_sapiens 0 7581
ENST00000302328 SCN11A-001 protein_coding Homo_sapiens 0 296
ENST00000303354 SCN9A-201 protein_coding Homo_sapiens 0 2386
ENST00000303395 SCN1A-001 protein_coding Homo_sapiens 0 3304
ENST00000333535 SCN5A-014 protein_coding Homo_sapiens 0 1079
ENST00000354534 SCN8A-001 protein_coding Homo_sapiens 0 472
ENST00000355133 SCN8A-005 protein_coding Homo_sapiens 0 472
ENST00000360093 SCN3A-201 protein_coding Homo_sapiens 0 5101
ENST00000375405 SCN1A-002 protein_coding Homo_sapiens 0 4778
ENST00000375427 SCN2A-002 protein_coding Homo_sapiens 0 7692
ENST00000375437 SCN2A-201 protein_coding Homo_sapiens 0 7581
ENST00000409050 SCN1A-003 protein_coding Homo_sapiens 0 3306
ENST00000409101 SCN3A-002 protein_coding Homo_sapiens 0 3387
ENST00000409435 SCN9A-004 protein_coding Homo_sapiens 0 2386
ENST00000409672 SCN9A-001 protein_coding Homo_sapiens 0 2730
ENST00000413689 SCN5A-001 protein_coding Homo_sapiens 0 1079
ENST00000414099 SCN5A-004 protein_coding Homo_sapiens 0 809
ENST00000423058 SCN1A-201 protein_coding Homo_sapiens 0 3304
ENST00000423572 SCN5A-003 protein_coding Homo_sapiens 0 1079
ENST00000424833 SCN2A-003 protein_coding Homo_sapiens 0 2093
ENST00000425664 SCN5A-201 protein_coding Homo_sapiens 0 809
ENST00000435607 SCN4A-201 protein_coding Homo_sapiens 0 1199
ENST00000440431 SCN3A-004 protein_coding Homo_sapiens 0 1628
ENST00000443581 SCN5A-202 protein_coding Homo_sapiens 0 1079
ENST00000444237 SCN11A-002 protein_coding Homo_sapiens 0 281
ENST00000449082 SCN10A-001 protein_coding Homo_sapiens 0 784
ENST00000449557 SCN5A-010 protein_coding Homo_sapiens 0 1079
ENST00000450102 SCN5A-008 protein_coding Homo_sapiens 0 1079
ENST00000451551 SCN5A-203 protein_coding Homo_sapiens 0 1079
ENST00000453007 SCN3A-003 protein_coding Homo_sapiens 0 649
ENST00000455624 SCN5A-002 protein_coding Homo_sapiens 0 564
ENST00000456224 SCN11A-003 protein_coding Homo_sapiens 0 296
ENST00000465043 SCN3A-007 processed_transcript Homo_sapiens 0 254
ENST00000472119 SCN9A-006 retained_intron Homo_sapiens 0 405
ENST00000473295 SCN1A-005 retained_intron Homo_sapiens 0 287
ENST00000480032 SCN2A-005 retained_intron Homo_sapiens 0 4870
ENST00000484898 SCN3A-008 processed_transcript Homo_sapiens 5.60519e-45 183
ENST00000486878 SCN2A-004 retained_intron Homo_sapiens 0 573
ENST00000507401 SCN1A-007 retained_intron Homo_sapiens 0 331
ENST00000545061 SCN8A-201 protein_coding Homo_sapiens 0 472
ENST00000578147 SCN4A-001 protein_coding Homo_sapiens 0 1188
ENST00000599343 SCN8A-202 protein_coding Homo_sapiens 0 477

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