C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000103010 Lyn-002 ENSMUSG00000042228 10090 + 4:3678127-3791612 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000103010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000103010 4.868±0.65 5.322±0.82 1.805±0.12 0.546±0.27 6.977±2.37 4.896±0.54 2.107±0.29 3.417±0.67 3.312±1.15 13.060±2.19 0.434±0.24 3.266±1.32 1.893±0.47 0.170±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009D CIL_00009D_0002 CGP 4:3574875-3813122
CIL_0001U6 CIL_0001U6_0002 CGP 4:3678115-3835665

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001782 IMP B cell homeostasis
GO:0001817 IMP regulation of cytokine production
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0002431 IMP Fc receptor mediated stimulatory signaling pathway
GO:0002513 IMP tolerance induction to self antigen
GO:0002576 IMP platelet degranulation
GO:0002762 IMP negative regulation of myeloid leukocyte differentiation
GO:0002768 IMP immune response-regulating cell surface receptor signaling pathway
GO:0002774 IMP Fc receptor mediated inhibitory signaling pathway
GO:0002902 IMP regulation of B cell apoptotic process
GO:0004672 IDA protein kinase activity
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005128 TAS erythropoietin receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007165 TAS signal transduction
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009725 IDA response to hormone
GO:0017124 IPI SH3 domain binding
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0030097 IMP hemopoiesis
GO:0030218 IMP erythrocyte differentiation
GO:0030335 IMP positive regulation of cell migration
GO:0030889 IMP negative regulation of B cell proliferation
GO:0031175 IMP neuron projection development
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0032403 IPI protein complex binding
GO:0033003 IMP regulation of mast cell activation
GO:0034136 IMP negative regulation of toll-like receptor 2 signaling pathway
GO:0034144 IMP negative regulation of toll-like receptor 4 signaling pathway
GO:0035556 IDA intracellular signal transduction
GO:0042531 IMP positive regulation of tyrosine phosphorylation of STAT protein
GO:0042541 TAS hemoglobin biosynthetic process
GO:0043304 IMP regulation of mast cell degranulation
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0043552 IMP positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 IEA innate immune response
GO:0045646 IMP regulation of erythrocyte differentiation
GO:0046777 IDA protein autophosphorylation
GO:0050707 IMP regulation of cytokine secretion
GO:0050727 IMP regulation of inflammatory response
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050853 IDA B cell receptor signaling pathway
GO:0050855 IMP regulation of B cell receptor signaling pathway
GO:0050861 IGI positive regulation of B cell receptor signaling pathway
GO:0051279 IGI regulation of release of sequestered calcium ion into cytosol
GO:0070372 IMP regulation of ERK1 and ERK2 cascade
GO:0070373 IMP negative regulation of ERK1 and ERK2 cascade
GO:0070667 IMP negative regulation of mast cell proliferation
GO:0090330 IMP regulation of platelet aggregation
GO:0097028 IMP dendritic cell differentiation
GO:1902532 IMP negative regulation of intracellular signal transduction
GO:2000670 IMP positive regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000519728 LYN-002 protein_coding Homo_sapiens 0 1725
ENST00000520220 LYN-003 protein_coding Homo_sapiens 0 1869

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