C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutathione peroxidase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105372 Gpx4-001 ENSMUSG00000075706 10090 + 10:80053488-80056439 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000105372
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000105372 157.006±80.37 223.375±47.75 67.947±18.77 47.987±12.27 171.886±26.84 69.435±8.25 110.640±30.63 204.579±14.66 84.244±31.38 95.034±17.44 161.847±19.23 74.367±23.27 136.482±10.81 768.107±518.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0002 VISTA 10:79539861-80142369
CIL_0000QU CIL_0000QU_0002 CGP 10:80035949-80056439
CIL_0000QT CIL_0000QT_0002 CGP 10:80047166-80102698

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004602 IDA glutathione peroxidase activity
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005829 IDA cytosol
GO:0006325 IDA chromatin organization
GO:0006979 IEA response to oxidative stress
GO:0007275 IEA multicellular organismal development
GO:0007283 IDA spermatogenesis
GO:0047066 IEA phospholipid-hydroperoxide glutathione peroxidase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000354171 GPX4-002 protein_coding Homo_sapiens 0 828
ENST00000585362 GPX4-004 protein_coding Homo_sapiens 0 383
ENST00000587648 GPX4-009 protein_coding Homo_sapiens 0 588
ENST00000587932 GPX4-005 retained_intron Homo_sapiens 0 206
ENST00000588919 GPX4-003 protein_coding Homo_sapiens 0 664
ENST00000589115 GPX4-007 protein_coding Homo_sapiens 0 654
ENST00000592940 GPX4-001 retained_intron Homo_sapiens 0 399
ENST00000593032 GPX4-006 protein_coding Homo_sapiens 0 496
ENST00000611653 GPX4-011 protein_coding Homo_sapiens 0 765
ENST00000614791 GPX4-010 protein_coding Homo_sapiens 0 224
ENST00000616066 GPX4-201 protein_coding Homo_sapiens 0 813
ENST00000622390 GPX4-202 protein_coding Homo_sapiens 0 688

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