C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin II
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000105932 Ins2-005 ENSMUSG00000000215 10090 - 7:142678661-142679717 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000105932
Transcript ID Adipose Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000105932 0.181±0.00 0.268±0.00 0.374±0.08 37.898±3.15 0.290±0.11 0.586±0.61 0.230±0.00 0.182±0.00 0.217±0.17 0.159±0.03 0.145±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MR CIL_0008MR_0002 VISTA 7:142247512-142849546
CIL_0007RG CIL_0007RG_0002 VISTA 7:142251566-142854813
CIL_00097V CIL_00097V_0002 VISTA 7:142268912-142873912

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000187 IDA activation of MAPK activity
GO:0005179 IEA hormone activity
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005732 IDA small nucleolar ribonucleoprotein complex
GO:0005737 IDA cytoplasm
GO:0006006 IMP glucose metabolic process
GO:0006983 IMP ER overload response
GO:0007520 IGI myoblast fusion
GO:0008286 IDA insulin receptor signaling pathway
GO:0010468 IDA regulation of gene expression
GO:0014902 IGI myotube differentiation
GO:0015758 TAS glucose transport
GO:0016042 IDA lipid catabolic process
GO:0030141 IDA secretory granule
GO:0034774 TAS secretory granule lumen
GO:0042325 IDA regulation of phosphorylation
GO:0043393 IDA regulation of protein binding
GO:0043552 IDA positive regulation of phosphatidylinositol 3-kinase activity
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0060070 IGI canonical Wnt signaling pathway
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000250971 INS-002 protein_coding Homo_sapiens 0 311
ENST00000381330 INS-001 protein_coding Homo_sapiens 0 311
ENST00000397262 INS-003 protein_coding Homo_sapiens 0 311
ENST00000512523 INS-006 protein_coding Homo_sapiens 4e-32 141

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