C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: sphingosine kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000106388 Sphk1-003 ENSMUSG00000061878 10090 + 11:116530925-116536657 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; HeartOvaryPlacentaENSMUST00000106388
Transcript ID Heart Ovary Placenta
ENSMUST00000106388 0.326±0.00 1.017±0.36 1.548±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008WF CIL_0008WF_0002 VISTA 11:116019003-116619995
CIL_00009I CIL_00009I_0002 CGP 11:116470845-116536674
CIL_00079O CIL_00079O_0002 CGP 11:116530925-116581447

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0001568 IGI blood vessel development
GO:0003677 ISA DNA binding
GO:0003951 IEA NAD+ kinase activity
GO:0004143 IEA diacylglycerol kinase activity
GO:0005516 ISA calmodulin binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0006670 ISS sphingosine metabolic process
GO:0006954 IMP inflammatory response
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007420 IGI brain development
GO:0008284 IGI positive regulation of cell proliferation
GO:0008481 ISA sphinganine kinase activity
GO:0010803 ISS regulation of tumor necrosis factor-mediated signaling pathway
GO:0017050 ISS D-erythro-sphingosine kinase activity
GO:0031398 ISS positive regulation of protein ubiquitination
GO:0032651 IMP regulation of interleukin-1 beta production
GO:0042346 ISS positive regulation of NF-kappaB import into nucleus
GO:0046834 ISA:IEA lipid phosphorylation
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity

Homologs

No Homologs available.

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