C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leptin receptor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000106921 Lepr-004 ENSMUSG00000057722 10090 + 4:101717404-101813667 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000106921
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000106921 2.452±1.44 0.463±0.21 6.899±0.64 0.685±0.00 1.356±0.11 0.995±0.28 0.408±0.05 1.755±0.42 0.514±0.50 8.928±1.34 0.260±0.11 2.549±1.12 8.799±8.56 0.055±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000264 CIL_000264_0002 CGP 4:101647718-101815352

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004888 TAS transmembrane signaling receptor activity
GO:0004896 IEA cytokine receptor activity
GO:0005515 IPI protein binding
GO:0005576 IEA extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0008203 IGI cholesterol metabolic process
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019222 TAS regulation of metabolic process
GO:0043235 ISO receptor complex
GO:0045721 IMP negative regulation of gluconeogenesis
GO:0051346 IGI negative regulation of hydrolase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000344610 LEPR-201 protein_coding Homo_sapiens 0 2316
ENST00000349533 LEPR-001 protein_coding Homo_sapiens 0 2311
ENST00000371058 LEPR-005 protein_coding Homo_sapiens 0 2311
ENST00000371059 LEPR-003 protein_coding Homo_sapiens 0 2313
ENST00000371060 LEPR-002 protein_coding Homo_sapiens 0 2451
ENST00000462765 LEPR-004 processed_transcript Homo_sapiens 0 1753
ENST00000471762 LEPR-006 processed_transcript Homo_sapiens 0 270
ENST00000616738 LEPR-203 protein_coding Homo_sapiens 0 2455

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