C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transducin-like enhancer of split 1, homolog of Drosophila E(spl)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107337 Tle1-002 ENSMUSG00000008305 10090 - 4:72157580-72200862 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000107337
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000107337 10.127±1.69 7.993±1.58 6.551±0.08 13.283±0.00 5.363±0.70 6.546±1.60 0.938±0.01 3.047±1.08 9.760±4.06 7.597±1.54 2.732±0.56 11.474±2.79 2.620±0.95 2.386±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KE CIL_0007KE_0004 UCNEbase 4:70810873-73489292
CIL_00090V CIL_00090V_0002 VISTA 4:71539683-72141070
CIL_0008X3 CIL_0008X3_0002 VISTA 4:71768926-72369840
CIL_0009AO CIL_0009AO_0002 VISTA 4:71866327-72468960
CIL_0008C4 CIL_0008C4_0002 VISTA 4:71896487-72497365
CIL_0008TV CIL_0008TV_0002 VISTA 4:72081989-72683115

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0016055 IEA Wnt signaling pathway
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000376463 TLE1-005 protein_coding Homo_sapiens 0 1513
ENST00000376472 TLE1-201 protein_coding Homo_sapiens 0 970
ENST00000376499 TLE1-001 protein_coding Homo_sapiens 0 1002
ENST00000418319 TLE1-002 protein_coding Homo_sapiens 0 689
ENST00000422965 TLE1P1-001 processed_pseudogene Homo_sapiens 0 883

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