C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000107538 Cdk12-001 ENSMUSG00000003119 10090 + 11:98203335-98251044 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000107538
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000107538 1.207±0.56 1.958±0.85 1.758±0.73 1.523±0.46 1.427±0.43 2.274±0.65 0.829±0.04 1.429±0.46 1.275±0.26 2.604±1.05 3.083±1.82 1.841±0.35

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SN CIL_0008SN_0002 VISTA 11:97857859-98458466
CIL_00080Z CIL_00080Z_0002 VISTA 11:98039002-98639485
CIL_00098W CIL_00098W_0002 VISTA 11:98077499-98680383
CIL_0007WH CIL_0007WH_0002 VISTA 11:98091902-98695006
CIL_0007D3 CIL_0007D3_0002 CGP 11:98152154-98278504
CIL_0007D4 CIL_0007D4_0002 CGP 11:98203059-98329648

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002944 IEA cyclin K-CDK12 complex
GO:0004672 ISS protein kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0006397 IEA mRNA processing
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0008380 ISS RNA splicing
GO:0016607 ISS nuclear speck
GO:0019908 ISS nuclear cyclin-dependent protein kinase holoenzyme complex
GO:0030332 IEA cyclin binding
GO:0043405 ISS regulation of MAP kinase activity
GO:0046777 ISS protein autophosphorylation
GO:0051726 IEA regulation of cell cycle
GO:0070816 ISS phosphorylation of RNA polymerase II C-terminal domain

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000430627 CDK12-008 protein_coding Homo_sapiens 0 5694
ENST00000447079 CDK12-001 protein_coding Homo_sapiens 0 5928
ENST00000559663 CDK12-002 nonsense_mediated_decay Homo_sapiens 0 560
ENST00000581593 CDK12-011 processed_transcript Homo_sapiens 0 444
ENST00000584336 CDK12-007 retained_intron Homo_sapiens 0 1212
ENST00000584632 CDK12-010 protein_coding Homo_sapiens 0 4470

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