C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109085 Gnas-014 ENSMUSG00000027523 10090 + 2:174330006-174346744 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonOvaryENSMUST00000109085
Transcript ID Adrenal Colon Ovary
ENSMUST00000109085 110.997±20.43 41.501±1.39 60.124±6.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00073J CIL_00073J_0002 CGP 2:174110349-174346744

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001894 IMP tissue homeostasis
GO:0001958 IMP endochondral ossification
GO:0003924 IBA GTPase activity
GO:0004871 ISS signal transducer activity
GO:0005159 IBA insulin-like growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005834 IBA heterotrimeric G-protein complex
GO:0006112 IMP energy reserve metabolic process
GO:0006184 IEA GTP catabolic process
GO:0006306 IMP DNA methylation
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007191 IGI adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007606 IBA sensory perception of chemical stimulus
GO:0009791 IMP post-embryonic development
GO:0016020 IDA membrane
GO:0030425 IDA dendrite
GO:0030819 ISS positive regulation of cAMP biosynthetic process
GO:0031683 IBA G-protein beta/gamma-subunit complex binding
GO:0031698 IBA beta-2 adrenergic receptor binding
GO:0031748 IBA D1 dopamine receptor binding
GO:0031852 IBA mu-type opioid receptor binding
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0035116 IMP embryonic hindlimb morphogenesis
GO:0035255 IBA ionotropic glutamate receptor binding
GO:0035264 IMP multicellular organism growth
GO:0040032 IMP post-embryonic body morphogenesis
GO:0042493 IMP response to drug
GO:0043588 IMP skin development
GO:0043950 ISS positive regulation of cAMP-mediated signaling
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0045672 IMP positive regulation of osteoclast differentiation
GO:0046872 IEA metal ion binding
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0051216 IMP cartilage development
GO:0051430 IBA corticotropin-releasing hormone receptor 1 binding
GO:0071514 IMP genetic imprinting
GO:0071880 ISS adenylate cyclase-activating adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000265620 GNAS-035 protein_coding Homo_sapiens 0 2237
ENST00000269162 GNAL-004 protein_coding Homo_sapiens 0 435
ENST00000306090 GNAS-201 protein_coding Homo_sapiens 0 588
ENST00000313949 GNAS-002 protein_coding Homo_sapiens 0 1834
ENST00000338783 GNAS-021 protein_coding Homo_sapiens 0 309
ENST00000349036 GNAS-037 protein_coding Homo_sapiens 0 425
ENST00000354359 GNAS-018 protein_coding Homo_sapiens 0 1834
ENST00000371075 GNAS-014 protein_coding Homo_sapiens 0 1834
ENST00000371081 GNAS-038 protein_coding Homo_sapiens 0 385
ENST00000371085 GNAS-015 protein_coding Homo_sapiens 0 1834
ENST00000371095 GNAS-017 protein_coding Homo_sapiens 0 2252
ENST00000371098 GNAS-025 protein_coding Homo_sapiens 3e-25 121
ENST00000371100 GNAS-001 protein_coding Homo_sapiens 0 1834
ENST00000371102 GNAS-009 protein_coding Homo_sapiens 0 1978
ENST00000419558 GNAS-023 protein_coding Homo_sapiens 0 527
ENST00000423027 GNAL-002 protein_coding Homo_sapiens 0 435
ENST00000423897 GNAS-049 protein_coding Homo_sapiens 6e-34 148
ENST00000450130 GNAS-036 protein_coding Homo_sapiens 0 584
ENST00000453292 GNAS-022 protein_coding Homo_sapiens 1e-30 137
ENST00000461152 GNAS-056 processed_transcript Homo_sapiens 0 198
ENST00000462499 GNAS-032 processed_transcript Homo_sapiens 0 364
ENST00000464624 GNAS-059 processed_transcript Homo_sapiens 0 1834
ENST00000464788 GNAS-054 processed_transcript Homo_sapiens 0 612
ENST00000464960 GNAS-040 processed_transcript Homo_sapiens 2e-25 121
ENST00000467227 GNAS-034 processed_transcript Homo_sapiens 0 636
ENST00000467321 GNAS-053 processed_transcript Homo_sapiens 0 702
ENST00000468895 GNAS-052 processed_transcript Homo_sapiens 0 815
ENST00000469431 GNAS-011 processed_transcript Homo_sapiens 0 488
ENST00000470512 GNAS-006 processed_transcript Homo_sapiens 0 913
ENST00000472183 GNAS-027 processed_transcript Homo_sapiens 0 619
ENST00000475610 GNAS-044 retained_intron Homo_sapiens 0 255
ENST00000476196 GNAS-041 retained_intron Homo_sapiens 0 1834
ENST00000476935 GNAS-030 processed_transcript Homo_sapiens 0 1018
ENST00000477931 GNAS-016 processed_transcript Homo_sapiens 0 1834
ENST00000478585 GNAS-008 processed_transcript Homo_sapiens 0 540
ENST00000479025 GNAS-045 retained_intron Homo_sapiens 0 335
ENST00000480232 GNAS-055 processed_transcript Homo_sapiens 0 966
ENST00000480975 GNAS-007 processed_transcript Homo_sapiens 0 1929
ENST00000481039 GNAS-004 processed_transcript Homo_sapiens 0 913
ENST00000481768 GNAS-012 processed_transcript Homo_sapiens 3e-25 121
ENST00000482112 GNAS-031 processed_transcript Homo_sapiens 0 667
ENST00000483387 GNAS-047 retained_intron Homo_sapiens 1e-25 121
ENST00000484504 GNAS-046 processed_transcript Homo_sapiens 4e-25 119
ENST00000485673 GNAS-005 processed_transcript Homo_sapiens 0 449
ENST00000487862 GNAS-019 retained_intron Homo_sapiens 0 1951
ENST00000487981 GNAS-057 retained_intron Homo_sapiens 0 604
ENST00000488546 GNAS-003 processed_transcript Homo_sapiens 0 1330
ENST00000488652 GNAS-029 processed_transcript Homo_sapiens 0 957
ENST00000490374 GNAS-033 processed_transcript Homo_sapiens 0 464
ENST00000491348 GNAS-026 processed_transcript Homo_sapiens 2e-25 121
ENST00000492907 GNAS-013 processed_transcript Homo_sapiens 0 1033
ENST00000493744 GNAS-048 processed_transcript Homo_sapiens 1e-25 121
ENST00000493958 GNAS-043 processed_transcript Homo_sapiens 0 503
ENST00000494081 GNAS-042 processed_transcript Homo_sapiens 0 453
ENST00000496934 GNAS-020 retained_intron Homo_sapiens 0 1834
ENST00000535121 GNAL-005 protein_coding Homo_sapiens 0 435
ENST00000603546 GNAS-063 protein_coding Homo_sapiens 0 440
ENST00000604005 GNAS-071 protein_coding Homo_sapiens 0 619

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