C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: Rous sarcoma oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000109529 Src-006 ENSMUSG00000027646 10090 + 2:157457085-157470355 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleENSMUST00000109529
Transcript ID Brain Muscle
ENSMUST00000109529 18.167±0.00 0.310±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006YE CIL_0006YE_0002 CGP 2:157367594-157471862
CIL_0006Y4 CIL_0006Y4_0002 CGP 2:157418444-157571274

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA protein kinase activity
GO:0004713 IMP protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005743 IEA mitochondrial inner membrane
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007049 IEA cell cycle
GO:0016301 IMP kinase activity
GO:0016477 IMP cell migration
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019904 IPI protein domain specific binding
GO:0020037 ISS heme binding
GO:0030900 IGI forebrain development
GO:0032587 IDA ruffle membrane
GO:0033146 IMP regulation of intracellular estrogen receptor signaling pathway
GO:0034446 IDA substrate adhesion-dependent cell spreading
GO:0035556 IGI intracellular signal transduction
GO:0036035 IGI osteoclast development
GO:0036120 IDA cellular response to platelet-derived growth factor stimulus
GO:0043393 IDA regulation of protein binding
GO:0045453 IMP bone resorption
GO:0046875 IPI ephrin receptor binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048477 IMP oogenesis
GO:0060065 IMP uterus development
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0060491 IGI regulation of cell projection assembly
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071803 IDA positive regulation of podosome assembly
GO:0090263 IGI positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000036635 fynb-001 protein_coding Danio_rerio 0 508
ENST00000358208 SRC-201 protein_coding Homo_sapiens 0 2004
ENST00000373558 SRC-005 protein_coding Homo_sapiens 0 2121
ENST00000373567 SRC-002 protein_coding Homo_sapiens 0 2004
ENST00000373578 SRC-001 protein_coding Homo_sapiens 0 2004
ENST00000472968 SRC-003 processed_transcript Homo_sapiens 0 333
ENST00000477066 SRC-004 processed_transcript Homo_sapiens 0 1147
ENST00000489153 SRC-006 processed_transcript Homo_sapiens 0 562
ENST00000493775 SRC-009 processed_transcript Homo_sapiens 0 342

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