C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin alpha 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112101 Itga6-002 ENSMUSG00000027111 10090 + 2:71786940-71856771 protein_coding

Mus musculus EnsemblGRCm38

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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112101
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112101 5.939±0.00 9.778±2.20 2.435±1.38 3.957±0.12 6.967±0.39 2.942±0.36 11.527±2.85 0.521±0.18 6.664±1.86 1.362±0.00 2.224±0.00 4.514±1.20 0.539±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008C9 CIL_0008C9_0002 VISTA 2:71216484-71818219
CIL_0009AY CIL_0009AY_0002 VISTA 2:71227336-71828847
CIL_0008AZ CIL_0008AZ_0002 VISTA 2:71235378-71836557
CIL_0008B0 CIL_0008B0_0002 VISTA 2:71237156-71838581
CIL_0003IK CIL_0003IK_0003 CGP 2:71543408-71858416
CIL_0004K8 CIL_0004K8_0002 CGP 2:71745616-71903858

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005178 IPI integrin binding
GO:0005515 IEA protein binding
GO:0005604 IDA basement membrane
GO:0005886 IDA plasma membrane
GO:0005913 IEA cell-cell adherens junction
GO:0005925 IEA focal adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008305 IDA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0009925 IDA basal plasma membrane
GO:0009986 IDA cell surface
GO:0010668 IEA ectodermal cell differentiation
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016323 IDA basolateral plasma membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0022409 IDA positive regulation of cell-cell adhesion
GO:0030056 IDA hemidesmosome
GO:0030175 IEA filopodium
GO:0031589 IEA cell-substrate adhesion
GO:0031668 IDA cellular response to extracellular stimulus
GO:0032403 IEA protein complex binding
GO:0033627 IDA cell adhesion mediated by integrin
GO:0034676 IEA integrin alpha6-beta4 complex
GO:0035878 IEA nail development
GO:0042327 IEA positive regulation of phosphorylation
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043065 IEA positive regulation of apoptotic process
GO:0043236 IEA laminin binding
GO:0043588 IEA skin development
GO:0045178 IDA basal part of cell
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046847 IMP filopodium assembly
GO:0046872 IEA metal ion binding
GO:0048565 IEA digestive tract development
GO:0050873 IDA brown fat cell differentiation
GO:0050900 IMP leukocyte migration
GO:0071407 IEA cellular response to organic cyclic compound
GO:0072001 IEA renal system development
GO:0097186 IEA amelogenesis
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264107 ITGA6-001 protein_coding Homo_sapiens 0 3472
ENST00000409080 ITGA6-004 protein_coding Homo_sapiens 0 3860
ENST00000409532 ITGA6-003 protein_coding Homo_sapiens 0 2593
ENST00000416789 ITGA6-006 protein_coding Homo_sapiens 0 723
ENST00000442250 ITGA6-010 protein_coding Homo_sapiens 0 2787
ENST00000458358 ITGA6-011 protein_coding Homo_sapiens 0 2787
ENST00000469534 ITGA6-007 retained_intron Homo_sapiens 0 385
ENST00000470259 ITGA6-008 retained_intron Homo_sapiens 0 189
ENST00000475302 ITGA6-009 retained_intron Homo_sapiens 0 531

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