C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transformation related protein 63
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115305 Trp63-006 ENSMUSG00000022510 10090 + 16:25801916-25877144 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverMuscleOvaryPlacentaENSMUST00000115305
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Muscle Ovary Placenta
ENSMUST00000115305 0.766±0.18 0.042±0.00 0.158±0.06 2.246±0.30 0.058±0.02 0.088±0.00 0.047±0.00 0.697±0.01 0.613±0.10 0.958±1.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Y5 CIL_0003Y5_0003 CGP 16:25286817-25892102
CIL_000933 CIL_000933_0002 VISTA 16:25287855-25888485
CIL_0000DP CIL_0000DP_0002 CGP 16:25683763-26105784

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0000989 IPI transcription factor binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001501 IMP skeletal system development
GO:0001736 IDA establishment of planar polarity
GO:0001738 IMP morphogenesis of a polarized epithelium
GO:0001942 IMP hair follicle development
GO:0002039 IBA p53 binding
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0002064 IDA epithelial cell development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003684 IDA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IBA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005667 IBA transcription factor complex
GO:0005829 IBA cytosol
GO:0006338 IMP chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006915 TAS apoptotic process
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007275 TAS multicellular organismal development
GO:0007389 IMP pattern specification process
GO:0007499 IMP ectoderm and mesoderm interaction
GO:0007569 IMP cell aging
GO:0008544 IMP epidermis development
GO:0009887 IMP organ morphogenesis
GO:0009954 IMP proximal/distal pattern formation
GO:0010165 IBA response to X-ray
GO:0010259 IMP multicellular organismal aging
GO:0010332 IBA response to gamma radiation
GO:0010481 IMP epidermal cell division
GO:0010838 IGI positive regulation of keratinocyte proliferation
GO:0030154 IMP cell differentiation
GO:0030216 IDA keratinocyte differentiation
GO:0030326 IMP embryonic limb morphogenesis
GO:0030425 IBA dendrite
GO:0030850 IMP prostate gland development
GO:0030855 IMP epithelial cell differentiation
GO:0030859 IMP polarized epithelial cell differentiation
GO:0031069 IMP hair follicle morphogenesis
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0036342 IMP post-anal tail morphogenesis
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042771 IMP intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043066 IMP negative regulation of apoptotic process
GO:0043281 IMP regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043523 IBA regulation of neuron apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0043589 IMP skin morphogenesis
GO:0043616 IDA keratinocyte proliferation
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045617 IGI negative regulation of keratinocyte differentiation
GO:0045747 IMP positive regulation of Notch signaling pathway
GO:0045944 IBA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048485 IMP sympathetic nervous system development
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048745 IMP smooth muscle tissue development
GO:0048807 IMP female genitalia morphogenesis
GO:0051262 IEA protein tetramerization
GO:0051402 IMP neuron apoptotic process
GO:0060157 IMP urinary bladder development
GO:0060197 IMP cloacal septation
GO:0060513 IMP prostatic bud formation
GO:0060529 IMP squamous basal epithelial stem cell differentiation involved in prostate gland acinus development
GO:2000381 IMP negative regulation of mesoderm development
GO:2001235 IDA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264731 TP63-001 protein_coding Homo_sapiens 0 1397
ENST00000320472 TP63-003 protein_coding Homo_sapiens 0 1397
ENST00000354600 TP63-004 protein_coding Homo_sapiens 0 1580
ENST00000392460 TP63-010 protein_coding Homo_sapiens 0 1397
ENST00000392461 TP63-015 protein_coding Homo_sapiens 0 1472
ENST00000392463 TP63-011 protein_coding Homo_sapiens 0 1472
ENST00000418709 TP63-002 protein_coding Homo_sapiens 0 1810
ENST00000434928 TP63-007 protein_coding Homo_sapiens 0 523
ENST00000437221 TP63-009 protein_coding Homo_sapiens 0 1884
ENST00000440651 TP63-008 protein_coding Homo_sapiens 0 1330
ENST00000449992 TP63-012 protein_coding Homo_sapiens 0 1037
ENST00000456148 TP63-013 protein_coding Homo_sapiens 0 1406
ENST00000460036 TP63-005 retained_intron Homo_sapiens 0 1537

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