C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphodiesterase 4A, cAMP specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000115458 Pde4a-002 ENSMUSG00000032177 10090 + 9:21184103-21211627 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaENSMUST00000115458
Transcript ID Adipose Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta
ENSMUST00000115458 1.347±0.28 3.052±0.49 7.910±0.00 1.949±0.58 0.780±0.24 4.759±0.00 0.415±0.18 1.043±0.05 2.538±0.00 1.093±0.34 0.571±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00037J CIL_00037J_0002 CGP 9:21138541-21213248
CIL_0004FB CIL_0004FB_0002 CGP 9:21165714-21239332

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004114 IDA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 ISS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005737 IDA cytoplasm
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0007608 IGI sensory perception of smell
GO:0010738 IMP regulation of protein kinase A signaling
GO:0035690 IDA cellular response to drug
GO:0043949 IMP regulation of cAMP-mediated signaling
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000006602 pde4a-001 protein_coding Danio_rerio 0 732
ENST00000262805 PDE4C-004 protein_coding Homo_sapiens 0 747
ENST00000293683 PDE4A-002 protein_coding Homo_sapiens 0 1301
ENST00000344979 PDE4A-004 protein_coding Homo_sapiens 0 1301
ENST00000355502 PDE4C-001 protein_coding Homo_sapiens 0 747
ENST00000380702 PDE4A-001 protein_coding Homo_sapiens 0 1301
ENST00000440014 PDE4A-003 protein_coding Homo_sapiens 0 1301
ENST00000447275 PDE4C-005 protein_coding Homo_sapiens 0 747
ENST00000539010 PDE4C-201 protein_coding Homo_sapiens 0 747
ENST00000586275 PDE4A-009 retained_intron Homo_sapiens 5e-39 165
ENST00000589073 PDE4A-006 nonsense_mediated_decay Homo_sapiens 0 350
ENST00000590407 PDE4A-007 retained_intron Homo_sapiens 0 1090
ENST00000591971 PDE4A-008 protein_coding Homo_sapiens 0 431
ENST00000592685 PDE4A-005 protein_coding Homo_sapiens 0 1301
ENST00000594465 PDE4C-003 protein_coding Homo_sapiens 0 747
ENST00000594617 PDE4C-002 protein_coding Homo_sapiens 0 747
ENST00000597297 PDE4C-007 protein_coding Homo_sapiens 0 747
ENST00000597360 PDE4C-006 retained_intron Homo_sapiens 0 747
ENST00000598111 PDE4C-008 protein_coding Homo_sapiens 0 625
ENST00000599188 PDE4C-009 nonsense_mediated_decay Homo_sapiens 0 747

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