C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: bromodomain containing 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000121285 Brd4-003 ENSMUSG00000024002 10090 - 17:32196274-32284109 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000121285
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000121285 2.812±0.76 1.276±0.00 6.347±4.57 12.778±7.31 3.013±1.08 5.055±0.00 1.820±0.40 3.545±1.46 4.138±2.83 3.757±1.33 2.943±0.77 10.541±6.45 15.993±9.05 1.958±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DW CIL_0004DW_0003 CGP 17:32183770-32284722
CIL_00043N CIL_00043N_0002 CGP 17:32196274-32321153

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000794 IDA condensed nuclear chromosome
GO:0001833 IMP inner cell mass cell proliferation
GO:0002039 ISS p53 binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IPI protein phosphorylation
GO:0007059 IMP chromosome segregation
GO:0008024 IDA positive transcription elongation factor complex b
GO:0032968 ISS positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043388 IDA positive regulation of DNA binding
GO:0043983 IMP histone H4-K12 acetylation
GO:0044154 IMP histone H3-K14 acetylation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0050727 ISS regulation of inflammatory response
GO:0070577 ISS lysine-acetylated histone binding
GO:1901407 ISS regulation of phosphorylation of RNA polymerase II C-terminal domain

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000114343 brd4-201 protein_coding Danio_rerio 0 276
ENSDART00000115117 brd4-001 protein_coding Danio_rerio 0 276
ENST00000263377 BRD4-001 protein_coding Homo_sapiens 0 4072
ENST00000360016 BRD4-003 protein_coding Homo_sapiens 0 2826
ENST00000371835 BRD4-002 protein_coding Homo_sapiens 0 2826
ENST00000594841 BRD4-004 protein_coding Homo_sapiens 0 2348
ENST00000595926 BRD4-010 retained_intron Homo_sapiens 0 230
ENST00000597315 BRD4-005 nonsense_mediated_decay Homo_sapiens 0 745
ENST00000601071 BRD4-006 processed_transcript Homo_sapiens 0 497
ENST00000601941 BRD4-008 protein_coding Homo_sapiens 0 551

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