C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000130269 Map2k3-002 ENSMUSG00000018932 10090 + 11:60932066-60952794 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonKidneyLiverLungOvaryTestisENSMUST00000130269
Transcript ID Adrenal Brain Breast Colon Kidney Liver Lung Ovary Testis
ENSMUST00000130269 10.900±4.59 1.075±0.43 5.520±1.73 4.955±1.80 2.460±0.00 5.555±1.77 4.014±0.95 1.657±0.00 1.502±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00013Z CIL_00013Z_0002 CGP 11:60902246-60952811
CIL_000142 CIL_000142_0002 CGP 11:60932033-61071131

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IMP MAPK cascade
GO:0000187 IMP activation of MAPK activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IMP MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0006954 IMP inflammatory response
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0042035 IMP regulation of cytokine biosynthetic process
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316920 MAP2K3-013 protein_coding Homo_sapiens 0 669
ENST00000342679 MAP2K3-001 protein_coding Homo_sapiens 0 730
ENST00000361818 MAP2K3-201 protein_coding Homo_sapiens 0 730
ENST00000395491 MAP2K3-002 nonsense_mediated_decay Homo_sapiens 0 730
ENST00000477540 MAP2K3-009 retained_intron Homo_sapiens 0 420
ENST00000479129 MAP2K3-006 nonsense_mediated_decay Homo_sapiens 0 300
ENST00000496046 MAP2K3-004 nonsense_mediated_decay Homo_sapiens 0 1435
ENST00000526076 MAP2K3-016 protein_coding Homo_sapiens 0 608
ENST00000527123 MAP2K3-014 protein_coding Homo_sapiens 0 246
ENST00000583508 MAP2K3-017 retained_intron Homo_sapiens 0 257
ENST00000613338 MAP2K3-202 protein_coding Homo_sapiens 0 730

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