C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: intersectin 1 (SH3 domain protein 1A)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000141625 Itsn1-018 ENSMUSG00000022957 10090 + 16:91899511-91909272 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00078C CIL_00078C_0002 CGP 16:91677268-91931687
CIL_0005TE CIL_0005TE_0002 CGP 16:91684398-91931687
CIL_00078A CIL_00078A_0002 CGP 16:91689322-91920597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0007264 IDA small GTPase mediated signal transduction
GO:0019209 IDA kinase activator activity
GO:0030027 IDA lamellipodium
GO:0030139 IDA endocytic vesicle
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0042327 IDA positive regulation of phosphorylation
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0051897 IDA positive regulation of protein kinase B signaling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000381284 ITSN1-004 protein_coding Homo_sapiens 0 483
ENST00000381285 ITSN1-202 protein_coding Homo_sapiens 0 483
ENST00000381318 ITSN1-001 protein_coding Homo_sapiens 0 483
ENST00000399367 ITSN1-023 protein_coding Homo_sapiens 0 483
ENST00000415023 ITSN1-005 protein_coding Homo_sapiens 0 682
ENST00000420666 ITSN1-031 nonsense_mediated_decay Homo_sapiens 0 335

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