C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Ca++ transporting, plasma membrane 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000143567 Atp2b4-001 ENSMUSG00000026463 10090 - 1:133699457-133801041 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryENSMUST00000143567
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary
ENSMUST00000143567 2.924±0.14 0.757±0.23 9.927±1.33 1.034±0.21 2.253±0.15 0.511±0.04 0.419±0.09 0.925±0.94 0.976±0.32 0.166±0.03 2.081±0.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W2 CIL_0008W2_0002 VISTA 1:133249313-133850886
CIL_00096T CIL_00096T_0002 VISTA 1:133444227-134045719
CIL_0005VX CIL_0005VX_0002 CGP 1:133699457-133907999

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005388 IEA calcium-transporting ATPase activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006816 TAS calcium ion transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0008152 IEA metabolic process
GO:0010751 IEA negative regulation of nitric oxide mediated signal transduction
GO:0030018 IEA Z disc
GO:0030315 IDA T-tubule
GO:0030346 IEA protein phosphatase 2B binding
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0036487 IEA nitric-oxide synthase inhibitor activity
GO:0042383 IDA sarcolemma
GO:0045019 IEA negative regulation of nitric oxide biosynthetic process
GO:0046872 IEA metal ion binding
GO:0050998 IEA nitric-oxide synthase binding
GO:0051001 IEA negative regulation of nitric-oxide synthase activity
GO:0051599 IEA response to hydrostatic pressure
GO:0070588 IEA calcium ion transmembrane transport
GO:0070885 IEA negative regulation of calcineurin-NFAT signaling cascade
GO:0071872 IEA cellular response to epinephrine stimulus
GO:0098736 IEA negative regulation of the force of heart contraction
GO:1900082 IEA negative regulation of arginine catabolic process
GO:1901205 IEA negative regulation of adrenergic receptor signaling pathway involved in heart process
GO:1903243 IMP negative regulation of cardiac muscle hypertrophy in response to stress
GO:1903249 IEA negative regulation of citrulline biosynthetic process
GO:2000481 IEA positive regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263519 ATP2B3-201 protein_coding Homo_sapiens 0 1461
ENST00000341360 ATP2B4-002 protein_coding Homo_sapiens 0 3770
ENST00000349466 ATP2B3-002 protein_coding Homo_sapiens 0 1461
ENST00000352432 ATP2B2-001 protein_coding Homo_sapiens 0 1164
ENST00000357681 ATP2B4-001 protein_coding Homo_sapiens 0 4250
ENST00000359149 ATP2B3-006 protein_coding Homo_sapiens 0 1458
ENST00000360273 ATP2B2-201 protein_coding Homo_sapiens 0 1164
ENST00000367218 ATP2B4-201 protein_coding Homo_sapiens 0 4141
ENST00000370186 ATP2B3-001 protein_coding Homo_sapiens 0 1151
ENST00000383800 ATP2B2-002 protein_coding Homo_sapiens 0 1164
ENST00000393842 ATP2B3-004 protein_coding Homo_sapiens 0 1151
ENST00000397077 ATP2B2-005 protein_coding Homo_sapiens 0 1164
ENST00000452124 ATP2B2-003 protein_coding Homo_sapiens 0 1424
ENST00000460129 ATP2B2-004 nonsense_mediated_decay Homo_sapiens 0 1160
ENST00000460549 ATP2B3-003 processed_transcript Homo_sapiens 0 261
ENST00000484746 ATP2B4-003 nonsense_mediated_decay Homo_sapiens 0 556

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