C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Transcript Info |
||||||
| Description: | Rho guanine nucleotide exchange factor (GEF) 4 | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENSMUST00000159747  |
Arhgef4-004 |
ENSMUSG00000037509 |
10090 | + |
1:34678188-34812739  |
protein_coding |
Expression PatternsNo expression data. |
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_0001J9 | CIL_0001J9_0002 | CGP | 1:34579727-34813309 |
| CIL_0001J8 | CIL_0001J8_0002 | CGP | 1:34678188-34843065 |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0005085 | ISS | guanyl-nucleotide exchange factor activity |
| GO:0005089 | IEA | Rho guanyl-nucleotide exchange factor activity |
| GO:0005737 | IEA | cytoplasm |
| GO:0030032 | ISS | lamellipodium assembly |
| GO:0030676 | ISS | Rac guanyl-nucleotide exchange factor activity |
| GO:0032321 | IEA | positive regulation of Rho GTPase activity |
| GO:0032855 | ISS | positive regulation of Rac GTPase activity |
| GO:0035556 | IEA | intracellular signal transduction |
| GO:0043547 | ISS | positive regulation of GTPase activity |
| GO:0046847 | ISS | filopodium assembly |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSDART00000057216
|
arhgef4-002 | protein_coding | Danio_rerio | 0 | 760 |
|
ENSDART00000133708
|
arhgef4-001 | protein_coding | Danio_rerio | 0 | 760 |
|
ENSDART00000152031
|
arhgef4-003 | protein_coding | Danio_rerio | 0 | 725 |
|
ENST00000326016
|
ARHGEF4-001 | protein_coding | Homo_sapiens | 0 | 2056 |
|
ENST00000343003
|
SPATA13-201 | protein_coding | Homo_sapiens | 0 | 429 |
|
ENST00000355771
|
ARHGEF4-009 | protein_coding | Homo_sapiens | 0 | 1929 |
|
ENST00000382095
|
SPATA13-001 | protein_coding | Homo_sapiens | 0 | 429 |
|
ENST00000382108
|
SPATA13-202 | protein_coding | Homo_sapiens | 0 | 429 |
|
ENST00000382141
|
RP11-307N16.6-001 | nonsense_mediated_decay | Homo_sapiens | 0 | 429 |
|
ENST00000392953
|
ARHGEF4-201 | protein_coding | Homo_sapiens | 0 | 2043 |
|
ENST00000399949
|
SPATA13-006 | protein_coding | Homo_sapiens | 0 | 429 |
|
ENST00000409126
|
SPATA13-011 | protein_coding | Homo_sapiens | 0 | 241 |
|
ENST00000409303
|
ARHGEF4-005 | protein_coding | Homo_sapiens | 0 | 1219 |
|
ENST00000424834
|
SPATA13-008 | protein_coding | Homo_sapiens | 0 | 429 |
|
ENST00000434675
|
SPATA13-010 | protein_coding | Homo_sapiens | 0 | 241 |
|
ENST00000439368
|
ARHGEF4-010 | processed_transcript | Homo_sapiens | 0 | 662 |
|
ENST00000490728
|
ARHGEF4-006 | retained_intron | Homo_sapiens | 0 | 889 |
|
ENST00000496764
|
ARHGEF4-007 | processed_transcript | Homo_sapiens | 0 | 243 |
|
ENST00000525092
|
ARHGEF4-014 | retained_intron | Homo_sapiens | 0 | 353 |
|
ENST00000525839
|
ARHGEF4-002 | protein_coding | Homo_sapiens | 0 | 1925 |
|
ENST00000527365
|
ARHGEF4-013 | retained_intron | Homo_sapiens | 0 | 564 |
|
ENST00000528247
|
ARHGEF4-011 | processed_transcript | Homo_sapiens | 0 | 568 |
|
ENST00000532720
|
ARHGEF4-012 | protein_coding | Homo_sapiens | 0 | 1027 |
|
ENST00000611048
|
ARHGEF4-203 | protein_coding | Homo_sapiens | 0 | 1219 |
