C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: GLI-Kruppel family member GLI2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000161451 Gli2-004 ENSMUSG00000048402 10090 - 1:118848462-119053339 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverTestisENSMUST00000161451
Transcript ID Kidney Liver Testis
ENSMUST00000161451 0.063±0.00 0.054±0.00 0.313±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TZ CIL_0007TZ_0002 VISTA 1:118476526-119078049
CIL_00081M CIL_00081M_0003 VISTA 1:118688411-119294612

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0001501 IMP skeletal system development
GO:0001649 IGI osteoblast differentiation
GO:0001701 IMP in utero embryonic development
GO:0001822 IGI kidney development
GO:0002009 IMP morphogenesis of an epithelium
GO:0002062 IGI chondrocyte differentiation
GO:0002076 IDA osteoblast development
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IGI cytoplasm
GO:0005929 IDA cilium
GO:0007224 IGI smoothened signaling pathway
GO:0007389 IGI pattern specification process
GO:0007411 IMP axon guidance
GO:0007418 IGI ventral midline development
GO:0007442 IGI hindgut morphogenesis
GO:0007507 IGI heart development
GO:0008283 IGI cell proliferation
GO:0008284 IGI positive regulation of cell proliferation
GO:0008589 IMP regulation of smoothened signaling pathway
GO:0009953 IGI dorsal/ventral pattern formation
GO:0009954 IGI proximal/distal pattern formation
GO:0016020 IDA membrane
GO:0016607 IDA nuclear speck
GO:0021508 IMP floor plate formation
GO:0021513 IMP spinal cord dorsal/ventral patterning
GO:0021517 IMP ventral spinal cord development
GO:0021522 IMP spinal cord motor neuron differentiation
GO:0021696 IGI cerebellar cortex morphogenesis
GO:0021775 IGI smoothened signaling pathway involved in ventral spinal cord interneuron specification
GO:0021776 IGI smoothened signaling pathway involved in spinal cord motor neuron cell fate specification
GO:0021904 IMP dorsal/ventral neural tube patterning
GO:0021915 IMP neural tube development
GO:0021938 IGI smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation
GO:0021965 IMP spinal cord ventral commissure morphogenesis
GO:0021983 IGI pituitary gland development
GO:0030154 IMP cell differentiation
GO:0030324 IGI lung development
GO:0030879 IMP mammary gland development
GO:0030902 IGI hindbrain development
GO:0031512 IDA motile primary cilium
GO:0032331 IMP negative regulation of chondrocyte differentiation
GO:0035295 IGI tube development
GO:0042475 IGI odontogenesis of dentin-containing tooth
GO:0042733 IMP embryonic digit morphogenesis
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045666 IGI positive regulation of neuron differentiation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048566 IMP embryonic digestive tract development
GO:0048589 IMP developmental growth
GO:0048646 IGI anatomical structure formation involved in morphogenesis
GO:0048666 IMP neuron development
GO:0048754 IMP branching morphogenesis of an epithelial tube
GO:0048856 IGI anatomical structure development
GO:0060032 IGI notochord regression
GO:0060322 IMP head development
GO:0060513 IMP prostatic bud formation
GO:0060603 IMP mammary gland duct morphogenesis
GO:0060831 IGI smoothened signaling pathway involved in dorsal/ventral neural tube patterning
GO:0071407 IDA cellular response to organic cyclic compound
GO:0072372 IDA primary cilium
GO:0090103 IMP cochlea morphogenesis
GO:0097542 IDA ciliary tip

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000314490 GLI2-201 protein_coding Homo_sapiens 0 375
ENST00000341310 GLI2-006 nonsense_mediated_decay Homo_sapiens 0 460
ENST00000361492 GLI2-202 protein_coding Homo_sapiens 0 558
ENST00000433812 GLI2-011 nonsense_mediated_decay Homo_sapiens 0 643
ENST00000435313 GLI2-008 processed_transcript Homo_sapiens 0 643
ENST00000437950 GLI2-004 nonsense_mediated_decay Homo_sapiens 0 375
ENST00000438299 GLI2-001 nonsense_mediated_decay Homo_sapiens 0 375
ENST00000445186 GLI2-005 nonsense_mediated_decay Homo_sapiens 0 375
ENST00000452319 GLI2-009 protein_coding Homo_sapiens 0 558
ENST00000452692 GLI2-002 nonsense_mediated_decay Homo_sapiens 0 460

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