C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000163322 Kcnma1-205 ENSMUSG00000063142 10090 - 14:23309015-23803304 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000163322
Transcript ID Adipose Bladder Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000163322 0.700±0.49 3.831±0.00 1.189±0.60 3.855±1.44 0.333±0.17 0.031±0.03 0.288±0.00 8.409±2.07 0.018±0.01 0.512±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JX CIL_0007JX_0002 UCNEbase 14:21252402-23394598
CIL_0005E6 CIL_0005E6_0002 CGP 14:22019712-24004859
CIL_000928 CIL_000928_0002 VISTA 14:22714212-23323263
CIL_0008H2 CIL_0008H2_0002 VISTA 14:22740563-23341478
CIL_0008QZ CIL_0008QZ_0002 VISTA 14:22794627-23395917
CIL_0008KV CIL_0008KV_0002 VISTA 14:23186013-23786602
CIL_0008L3 CIL_0008L3_0002 VISTA 14:23193824-23794811
CIL_00087A CIL_00087A_0002 VISTA 14:23220146-23821598
CIL_0004CA CIL_0004CA_0002 CGP 14:23289431-24245920

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0005249 IMP voltage-gated potassium channel activity
GO:0005267 IGI potassium channel activity
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0006813 IDA potassium ion transport
GO:0007268 IMP synaptic transmission
GO:0007605 IMP sensory perception of sound
GO:0007623 IMP circadian rhythm
GO:0007628 IMP adult walking behavior
GO:0008076 IGI voltage-gated potassium channel complex
GO:0009897 IDA external side of plasma membrane
GO:0015269 IDA calcium-activated potassium channel activity
GO:0016021 IDA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0019228 IMP neuronal action potential
GO:0032344 IMP regulation of aldosterone metabolic process
GO:0042311 IMP vasodilation
GO:0042391 IMP regulation of membrane potential
GO:0042491 IMP auditory receptor cell differentiation
GO:0043195 IDA terminal bouton
GO:0045211 IDA postsynaptic membrane
GO:0045475 IMP locomotor rhythm
GO:0045794 IMP negative regulation of cell volume
GO:0046541 IGI saliva secretion
GO:0048469 IMP cell maturation
GO:0050885 IMP neuromuscular process controlling balance
GO:0051260 IDA protein homooligomerization
GO:0060072 IDA large conductance calcium-activated potassium channel activity
GO:0060073 IMP micturition
GO:0060082 IMP eye blink reflex
GO:0060083 IMP smooth muscle contraction involved in micturition
GO:0060087 IMP relaxation of vascular smooth muscle
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000143200 kcnma1a-001 protein_coding Danio_rerio 0 2344
ENSDART00000122557 kcnma1a-201 protein_coding Danio_rerio 0 1877
ENST00000286627 KCNMA1-001 protein_coding Homo_sapiens 0 4453
ENST00000286628 KCNMA1-009 protein_coding Homo_sapiens 0 2405
ENST00000354353 KCNMA1-201 protein_coding Homo_sapiens 0 2405
ENST00000372403 KCNMA1-004 protein_coding Homo_sapiens 0 4412
ENST00000372408 KCNMA1-005 protein_coding Homo_sapiens 0 4412
ENST00000372421 KCNMA1-002 protein_coding Homo_sapiens 0 4412
ENST00000372437 KCNMA1-006 protein_coding Homo_sapiens 0 2405
ENST00000372440 KCNMA1-003 protein_coding Homo_sapiens 0 4412
ENST00000372443 KCNMA1-010 protein_coding Homo_sapiens 0 3515
ENST00000404771 KCNMA1-008 protein_coding Homo_sapiens 0 2405
ENST00000404857 KCNMA1-202 protein_coding Homo_sapiens 0 4368
ENST00000406533 KCNMA1-203 protein_coding Homo_sapiens 0 3472
ENST00000428546 KCNMA1-019 protein_coding Homo_sapiens 0 725
ENST00000434208 KCNMA1-011 protein_coding Homo_sapiens 0 2049
ENST00000450795 KCNMA1-018 protein_coding Homo_sapiens 0 870
ENST00000457953 KCNMA1-007 protein_coding Homo_sapiens 0 2405
ENST00000475352 KCNMA1-012 processed_transcript Homo_sapiens 0 217
ENST00000484343 KCNMA1-017 processed_transcript Homo_sapiens 0 302
ENST00000484507 KCNMA1-016 processed_transcript Homo_sapiens 0 418
ENST00000604624 KCNMA1-020 protein_coding Homo_sapiens 0 4309

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