C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Pbx/knotted 1 homeobox
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000175806 Pknox1-003 ENSMUSG00000006705 10090 + 17:31564749-31605481 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000175806
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000175806 4.181±2.16 3.326±0.42 1.782±0.00 4.095±0.34 4.484±0.66 1.229±0.20 2.309±0.60 1.574±0.56 3.856±0.48 9.835±1.82 2.178±0.02 6.546±1.89

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QJ CIL_0008QJ_0002 VISTA 17:31053737-31653776
CIL_0000D3 CIL_0000D3_0002 CGP 17:31564749-31637199

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0003677 IDA DNA binding
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0030097 IMP hemopoiesis
GO:0030217 IMP T cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0043010 IMP camera-type eye development
GO:0043565 IDA sequence-specific DNA binding
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000053210 pknox1.1-001 protein_coding Danio_rerio 9e-17 94
ENSDART00000125032 pknox1.2-001 protein_coding Danio_rerio 0.00000000000001 86
ENST00000291547 PKNOX1-001 protein_coding Homo_sapiens 0 1618
ENST00000418336 PKNOX1-006 retained_intron Homo_sapiens 0 235
ENST00000432907 PKNOX1-201 protein_coding Homo_sapiens 0 1227
ENST00000474336 PKNOX1-003 retained_intron Homo_sapiens 0 370
ENST00000480179 PKNOX1-002 retained_intron Homo_sapiens 0 702
ENST00000557820 PKNOX1-008 processed_transcript Homo_sapiens 0 538
ENST00000558955 PKNOX1-009 retained_intron Homo_sapiens 0 575
ENST00000560448 PKNOX1-005 nonsense_mediated_decay Homo_sapiens 0 1227
ENST00000607150 PKNOX1-010 processed_transcript Homo_sapiens 0 309

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