C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: rho/rac guanine nucleotide exchange factor (GEF) 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000176539 Arhgef2-013 ENSMUSG00000028059 10090 + 3:88615367-88634499 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008P5 CIL_0008P5_0002 VISTA 3:88218217-88823366
CIL_000898 CIL_000898_0002 VISTA 3:88224783-88827970

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IDA cell morphogenesis
GO:0005089 IDA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0007015 IPI actin filament organization
GO:0008017 IDA microtubule binding
GO:0032321 IEA:IDA positive regulation of Rho GTPase activity
GO:0035023 IDA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0043025 IDA neuronal cell body
GO:0043198 IDA dendritic shaft

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000313667 ARHGEF2-002 protein_coding Homo_sapiens 0 950
ENST00000313695 ARHGEF2-003 protein_coding Homo_sapiens 0 944
ENST00000361247 ARHGEF2-001 protein_coding Homo_sapiens 0 957
ENST00000462460 ARHGEF2-004 protein_coding Homo_sapiens 0 1044
ENST00000465079 ARHGEF2-011 retained_intron Homo_sapiens 0 213
ENST00000470874 ARHGEF2-009 nonsense_mediated_decay Homo_sapiens 0 398
ENST00000471589 ARHGEF2-010 protein_coding Homo_sapiens 0 902
ENST00000476273 ARHGEF2-008 processed_transcript Homo_sapiens 0 387
ENST00000487755 ARHGEF2-006 retained_intron Homo_sapiens 0 217
ENST00000495070 ARHGEF2-005 protein_coding Homo_sapiens 1.99965e-42 176
ENST00000497907 ARHGEF2-012 protein_coding Homo_sapiens 0 848
ENST00000609707 ARHGEF2-018 protein_coding Homo_sapiens 0 656

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