C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NLR family, pyrin domain containing 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000183845 Nlrp6-001 ENSMUSG00000038745 10090 + 7:140920902-140929192 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000183845
Transcript ID Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000183845 0.032±0.00 0.078±0.00 14.483±1.75 0.016±0.00 10.170±1.89 15.467±0.85 0.083±0.05 0.266±0.20 0.179±0.00 0.044±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002B4 CIL_0002B4_0002 CGP 7:140920902-140947664

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005000 ISS vasopressin receptor activity
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007186 ISS G-protein coupled receptor signaling pathway
GO:0009617 IMP response to bacterium
GO:0010506 IMP regulation of autophagy
GO:0034122 IMP negative regulation of toll-like receptor signaling pathway
GO:0042060 IMP wound healing
GO:0043124 IMP negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043409 IMP negative regulation of MAPK cascade
GO:0050727 IMP regulation of inflammatory response
GO:0050777 IMP negative regulation of immune response
GO:0070255 IMP regulation of mucus secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000312165 NLRP6-001 protein_coding Homo_sapiens 0 1190
ENST00000527946 NLRP6-003 retained_intron Homo_sapiens 1e-30 137
ENST00000534750 NLRP6-002 protein_coding Homo_sapiens 0 1199

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