C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: telomeric repeat binding factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000188371 Terf1-001 ENSMUSG00000025925 10090 + 1:15805646-15844052 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000188371
Transcript ID Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000188371 0.645±0.01 0.598±0.00 0.409±0.11 0.206±0.00 0.292±0.00 1.190±0.43 0.936±0.28 0.390±0.05 0.850±0.22 1.333±0.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003GB CIL_0003GB_0002 CGP 1:15287254-15844052
CIL_000132 CIL_000132_0002 CGP 1:15805646-15892722

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 IEA G2/M transition of mitotic cell cycle
GO:0000723 IBA telomere maintenance
GO:0000783 IDA nuclear telomere cap complex
GO:0000784 IDA nuclear chromosome, telomeric region
GO:0001309 IEA age-dependent telomere shortening
GO:0003682 IEA chromatin binding
GO:0003691 ISS double-stranded telomeric DNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005819 IEA spindle
GO:0005856 IEA cytoskeleton
GO:0006919 IBA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007067 IEA mitotic nuclear division
GO:0007094 IEA mitotic spindle assembly checkpoint
GO:0008017 IEA microtubule binding
GO:0008156 IEA negative regulation of DNA replication
GO:0008301 IEA DNA binding, bending
GO:0010834 IEA telomere maintenance via telomere shortening
GO:0031116 IEA positive regulation of microtubule polymerization
GO:0032211 IEA negative regulation of telomere maintenance via telomerase
GO:0042162 IBA telomeric DNA binding
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0043065 IEA positive regulation of apoptotic process
GO:0045840 IEA positive regulation of mitosis
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0046982 IEA protein heterodimerization activity
GO:0051260 IEA protein homooligomerization
GO:0051974 IEA negative regulation of telomerase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000276602 TERF1-002 protein_coding Homo_sapiens 0 669
ENST00000276603 TERF1-001 protein_coding Homo_sapiens 0 841
ENST00000311003 TERF1P1-001 processed_pseudogene Homo_sapiens 0 619
ENST00000399580 TERF1P4-001 processed_pseudogene Homo_sapiens 0 774
ENST00000432946 RP11-311P8.2-001 processed_pseudogene Homo_sapiens 0 638
ENST00000477545 TERF1P5-001 processed_pseudogene Homo_sapiens 0 638
ENST00000505638 TERF1P3-001 processed_pseudogene Homo_sapiens 0 612
ENST00000517390 TERF1-006 protein_coding Homo_sapiens 0 532
ENST00000518874 TERF1-005 protein_coding Homo_sapiens 0 265

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