C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000007722 ITGA3-020 ENSG00000005884 9606 + 17:50056440-50089729 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleOvaryENST00000007722
Transcript ID Muscle Ovary
ENST00000007722 0.487±0.00 2.591±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QJ CIL_0007QJ_0001 VISTA 17:49459872-50061823
CIL_00088W CIL_00088W_0001 VISTA 17:49956976-50560219
CIL_0004N5 CIL_0004N5_0002 CGP 17:49990005-50090481

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0001948 IPI glycoprotein binding
GO:0001968 IEA fibronectin binding
GO:0002020 IPI protease binding
GO:0005178 IEA integrin binding
GO:0005515 IPI protein binding
GO:0005518 IEA collagen binding
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0007155 IEA cell adhesion
GO:0007160 TAS cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007507 IEA heart development
GO:0007596 TAS blood coagulation
GO:0007613 IEA memory
GO:0008305 TAS integrin complex
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010628 IEA positive regulation of gene expression
GO:0010634 IEA positive regulation of epithelial cell migration
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0010976 IEA positive regulation of neuron projection development
GO:0016323 IEA basolateral plasma membrane
GO:0017015 IMP regulation of transforming growth factor beta receptor signaling pathway
GO:0019904 IEA protein domain specific binding
GO:0030111 IMP regulation of Wnt signaling pathway
GO:0030198 TAS extracellular matrix organization
GO:0030324 IMP lung development
GO:0030426 IEA growth cone
GO:0030510 IMP regulation of BMP signaling pathway
GO:0031345 IEA negative regulation of cell projection organization
GO:0031527 IDA filopodium membrane
GO:0034667 IMP integrin alpha3-beta1 complex
GO:0034698 IEA response to gonadotropin
GO:0035024 IEA negative regulation of Rho protein signal transduction
GO:0035640 IEA exploration behavior
GO:0042493 IEA response to drug
GO:0043235 IDA receptor complex
GO:0043236 IEA laminin binding
GO:0043588 IMP skin development
GO:0044708 IEA single-organism behavior
GO:0045202 IEA synapse
GO:0046872 IEA metal ion binding
GO:0046982 IDA protein heterodimerization activity
GO:0048333 IEP mesodermal cell differentiation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050900 TAS leukocyte migration
GO:0060076 IEA excitatory synapse
GO:0060135 IEA maternal process involved in female pregnancy
GO:0070062 IDA extracellular vesicular exosome
GO:0071438 IDA invadopodium membrane
GO:0071944 IDA cell periphery
GO:0072006 IMP nephron development
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:0097060 IEA synaptic membrane
GO:0097062 IEA dendritic spine maintenance
GO:0097205 IMP renal filtration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000120375 Itga3-004 protein_coding Mus_musculus 0 3522
ENSMUST00000001548 Itga3-001 protein_coding Mus_musculus 0 3264
ENSMUST00000107739 Itga3-002 protein_coding Mus_musculus 0 3031
ENSMUST00000145671 Itga3-003 protein_coding Mus_musculus 0 645
ENSMUST00000141693 Itga3-006 retained_intron Mus_musculus 0 556

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