C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transcription factor AP-4 (activating enhancer binding protein 4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000204517 TFAP4-001 ENSG00000090447 9606 - 16:4257186-4273075 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000204517
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000204517 3.058±0.00 1.392±0.00 0.086±0.00 0.758±0.00 0.954±0.38 2.972±0.00 0.114±0.03 1.089±0.51 0.492±0.25 0.952±0.33 2.870±0.00 8.765±5.58 3.338±1.15 1.409±0.61

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00032P CIL_00032P_0001 CGP 16:4189374-4273075
CIL_0000WQ CIL_0000WQ_0001 CGP 16:4257186-4339597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006461 IDA protein complex assembly
GO:0006978 IDA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008285 IMP negative regulation of cell proliferation
GO:0010629 IEA negative regulation of gene expression
GO:0017053 ISS transcriptional repressor complex
GO:0042803 IPI protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043065 IDA positive regulation of apoptotic process
GO:0043392 IDA negative regulation of DNA binding
GO:0043565 IDA sequence-specific DNA binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0043923 IDA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0070888 IDA E-box binding
GO:0071157 IMP negative regulation of cell cycle arrest
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:2001269 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005862 Tfap4-201 protein_coding Mus_musculus 0 1986

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