C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transforming growth factor, beta receptor III
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000212355 TGFBR3-201 ENSG00000069702 9606 - 1:91680345-91886279 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000212355
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000212355 41.466±0.00 5.845±0.00 0.838±0.07 9.879±2.53 9.559±7.69 3.820±1.78 3.289±1.46 4.815±3.67 16.557±9.15 3.066±0.00 16.003±20.85 7.588±0.07 3.345±1.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069I CIL_00069I_0001 CGP 1:91500893-91906335
CIL_0008DI CIL_0008DI_0001 VISTA 1:91505983-92108430
CIL_0008YV CIL_0008YV_0001 VISTA 1:91545179-92146674
CIL_0005ZR CIL_0005ZR_0001 CGP 1:91680343-92014426

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001568 IEA blood vessel development
GO:0001666 IEA response to hypoxia
GO:0001701 IEA in utero embryonic development
GO:0001824 IEA blastocyst development
GO:0001837 IDA epithelial to mesenchymal transition
GO:0001889 ISS liver development
GO:0003007 ISS heart morphogenesis
GO:0005024 IDA transforming growth factor beta-activated receptor activity
GO:0005114 IDA type II transforming growth factor beta receptor binding
GO:0005160 ISS transforming growth factor beta receptor binding
GO:0005515 IPI protein binding
GO:0005539 ISS glycosaminoglycan binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0005783 IEA endoplasmic reticulum
GO:0005887 ISS integral component of plasma membrane
GO:0006461 IEA protein complex assembly
GO:0006955 IMP immune response
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0007181 IEA transforming growth factor beta receptor complex assembly
GO:0008201 ISS heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0010633 IEA negative regulation of epithelial cell migration
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0015026 IDA coreceptor activity
GO:0016049 ISS cell growth
GO:0016477 ISS cell migration
GO:0017134 IEA fibroblast growth factor binding
GO:0030165 ISS PDZ domain binding
GO:0030509 IDA BMP signaling pathway
GO:0030511 IEA positive regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0031100 IEA organ regeneration
GO:0032354 IDA response to follicle-stimulating hormone
GO:0034673 IDA inhibin-betaglycan-ActRII complex
GO:0034695 IDA response to prostaglandin E
GO:0034699 IDA response to luteinizing hormone
GO:0035556 IMP intracellular signal transduction
GO:0043393 IEA regulation of protein binding
GO:0046332 IMP SMAD binding
GO:0048185 IEA activin binding
GO:0050431 IDA transforming growth factor beta binding
GO:0050680 ISS negative regulation of epithelial cell proliferation
GO:0051092 IEA positive regulation of NF-kappaB transcription factor activity
GO:0051271 IDA negative regulation of cellular component movement
GO:0055010 ISS ventricular cardiac muscle tissue morphogenesis
GO:0060021 ISS palate development
GO:0060038 ISS cardiac muscle cell proliferation
GO:0060216 ISS definitive hemopoiesis
GO:0060317 IDA cardiac epithelial to mesenchymal transition
GO:0060318 ISS definitive erythrocyte differentiation
GO:0060347 ISS heart trabecula formation
GO:0060389 IMP pathway-restricted SMAD protein phosphorylation
GO:0070062 IDA extracellular vesicular exosome
GO:0070123 IDA transforming growth factor beta receptor activity, type III

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031224 Tgfbr3-001 protein_coding Mus_musculus 0 2529
ENSMUST00000138469 Tgfbr3-003 processed_transcript Mus_musculus 0 2259
ENSMUST00000146591 Tgfbr3-002 retained_intron Mus_musculus 0 946
ENSMUST00000136882 Tgfbr3-004 protein_coding Mus_musculus 0 409

Loading