C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000222673 OGDH-001 ENSG00000105953 9606 + 7:44606639-44709066 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000222673
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000222673 22.111±0.00 18.721±0.00 7.787±0.00 11.078±5.77 19.809±16.49 12.813±5.98 65.806±51.13 24.602±20.54 8.604±0.50 17.707±14.20 74.368±47.31 23.988±8.41 25.645±6.92 23.858±0.77

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J7 CIL_0000J7_0001 CGP 7:44577894-44709066
CIL_0000J8 CIL_0000J8_0001 CGP 7:44606572-44769881

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004591 IEA:ISS oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 IDA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006091 ISS generation of precursor metabolites and energy
GO:0006096 IEA glycolytic process
GO:0006099 TAS:IEA tricarboxylic acid cycle
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006104 IEA succinyl-CoA metabolic process
GO:0006554 TAS lysine catabolic process
GO:0006734 IEA NADH metabolic process
GO:0008152 IEA metabolic process
GO:0016624 IEA oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0021695 IEA cerebellar cortex development
GO:0021756 IEA striatum development
GO:0021766 IEA hippocampus development
GO:0021794 IEA thalamus development
GO:0021860 IEA pyramidal neuron development
GO:0022028 IEA tangential migration from the subventricular zone to the olfactory bulb
GO:0030976 IEA thiamine pyrophosphate binding
GO:0031072 IEA heat shock protein binding
GO:0031966 ISS mitochondrial membrane
GO:0034602 IEA oxoglutarate dehydrogenase (NAD+) activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045252 IEA oxoglutarate dehydrogenase complex
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0055114 IEA oxidation-reduction process
GO:0061034 IEA olfactory bulb mitral cell layer development

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003461 Ogdh-001 protein_coding Mus_musculus 0 3980
ENSMUST00000101554 Ogdh-004 protein_coding Mus_musculus 0 3967
ENSMUST00000081894 Ogdh-003 protein_coding Mus_musculus 0 3701
ENSMUST00000093350 Ogdh-002 protein_coding Mus_musculus 0 3188
ENSDART00000013485 ogdhb-201 protein_coding Danio_rerio 0 1788
ENSDART00000139214 ogdhb-001 protein_coding Danio_rerio 0 1788
ENSMUST00000140765 Ogdh-005 protein_coding Mus_musculus 0 523
ENSMUST00000135124 Ogdh-006 protein_coding Mus_musculus 0 381
ENSMUST00000125929 Ogdh-008 retained_intron Mus_musculus 0 353

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