C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: acid-sensing (proton-gated) ion channel 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000225823 ASIC2-001 ENSG00000108684 9606 - 17:33013087-33292988 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaENST00000225823
Transcript ID Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta
ENST00000225823 0.007±0.00 0.134±0.00 1.492±0.49 0.073±0.00 0.039±0.01 0.605±0.00 0.038±0.00 0.027±0.00 0.085±0.01 0.160±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074A CIL_00074A_0001 CGP 17:32970376-34174964

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003026 IEA regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback
GO:0005216 IEA ion channel activity
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005261 IEA cation channel activity
GO:0005272 IEA sodium channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006812 IEA cation transport
GO:0006814 IEA sodium ion transport
GO:0007268 TAS synaptic transmission
GO:0007417 TAS central nervous system development
GO:0007422 TAS peripheral nervous system development
GO:0007602 IEA phototransduction
GO:0007605 IEA sensory perception of sound
GO:0009612 IEA response to mechanical stimulus
GO:0010447 IEA response to acidic pH
GO:0010468 IMP regulation of gene expression
GO:0015280 IEA ligand-gated sodium channel activity
GO:0015672 TAS monovalent inorganic cation transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019229 IEA regulation of vasoconstriction
GO:0022839 IEA ion gated channel activity
GO:0030193 IMP regulation of blood coagulation
GO:0034220 TAS ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035418 IEA protein localization to synapse
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IEA regulation of membrane potential
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043066 IEA negative regulation of apoptotic process
GO:0043197 IEA dendritic spine
GO:0045202 IEA synapse
GO:0050915 IMP sensory perception of sour taste
GO:0050974 IEA detection of mechanical stimulus involved in sensory perception
GO:0051965 IEA positive regulation of synapse assembly
GO:0055085 TAS transmembrane transport
GO:0071229 IEA cellular response to acid
GO:0071468 IEA cellular response to acidity
GO:0098655 IEA cation transmembrane transport
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021045 Asic2-001 protein_coding Mus_musculus 0 3517
ENSMUST00000066197 Asic2-002 protein_coding Mus_musculus 0 1869
ENSDART00000105541 asic1a-201 protein_coding Danio_rerio 0 279
ENSDART00000004588 asic1a-001 protein_coding Danio_rerio 0 279

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