C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: histone deacetylase 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000225983 HDAC5-003 ENSG00000108840 9606 - 17:44076746-44123638 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonOvaryTestisENST00000225983
Transcript ID Breast Colon Ovary Testis
ENST00000225983 2.628±0.00 4.390±0.00 5.113±0.38 2.393±0.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B6 CIL_0009B6_0001 VISTA 17:43966083-44567774
CIL_0005J5 CIL_0005J5_0001 CGP 17:44070735-44123702
CIL_0005J4 CIL_0005J4_0001 CGP 17:44076746-44162476

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 TAS:IEA histone deacetylase complex
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001047 IDA core promoter binding
GO:0002076 IEA osteoblast development
GO:0003714 IEA transcription corepressor activity
GO:0004407 IDA:IEA histone deacetylase activity
GO:0005080 IPI protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 IEA cytosol
GO:0006325 TAS chromatin organization
GO:0006338 TAS chromatin remodeling
GO:0006342 TAS chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0006954 TAS inflammatory response
GO:0007219 TAS Notch signaling pathway
GO:0007507 IEA heart development
GO:0008134 IPI transcription factor binding
GO:0010830 ISS regulation of myotube differentiation
GO:0010832 IMP negative regulation of myotube differentiation
GO:0016568 TAS:IEA chromatin modification
GO:0016575 IDA histone deacetylation
GO:0016604 IEA nuclear body
GO:0030183 TAS B cell differentiation
GO:0032041 IEA NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0032869 NAS cellular response to insulin stimulus
GO:0033555 IEA multicellular organismal response to stress
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0042113 TAS B cell activation
GO:0042220 IEA response to cocaine
GO:0042493 IEA response to drug
GO:0043234 IEA protein complex
GO:0043393 IMP regulation of protein binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045892 TAS negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046969 IEA NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 IEA NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0048742 IEA regulation of skeletal muscle fiber development
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051153 IEA regulation of striated muscle cell differentiation
GO:0070491 IPI repressing transcription factor binding
GO:0070932 IEA histone H3 deacetylation
GO:0070933 IEA histone H4 deacetylation
GO:0090051 IMP negative regulation of cell migration involved in sprouting angiogenesis
GO:0097372 IEA NAD-dependent histone deacetylase activity (H3-K18 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107152 Hdac5-001 protein_coding Mus_musculus 0 5029
ENSMUST00000107150 Hdac5-019 protein_coding Mus_musculus 0 4987
ENSMUST00000008999 Hdac5-002 protein_coding Mus_musculus 0 4494
ENSMUST00000124077 Hdac5-007 nonsense_mediated_decay Mus_musculus 0 4394
ENSMUST00000107151 Hdac5-003 protein_coding Mus_musculus 0 3066
ENSMUST00000149087 Hdac5-020 retained_intron Mus_musculus 0 2135
ENSMUST00000150965 Hdac5-021 retained_intron Mus_musculus 0 1000
ENSMUST00000137787 Hdac5-014 retained_intron Mus_musculus 0 826
ENSMUST00000156337 Hdac5-005 protein_coding Mus_musculus 0 689
ENSMUST00000140481 Hdac5-013 retained_intron Mus_musculus 0 623
ENSMUST00000125072 Hdac5-004 processed_transcript Mus_musculus 0 532
ENSMUST00000136304 Hdac5-015 retained_intron Mus_musculus 0 527
ENSMUST00000133651 Hdac5-010 retained_intron Mus_musculus 0 525
ENSMUST00000128686 Hdac5-006 processed_transcript Mus_musculus 0 521
ENSMUST00000126453 Hdac5-011 retained_intron Mus_musculus 0 481
ENSMUST00000140962 Hdac5-018 protein_coding Mus_musculus 0 416
ENSMUST00000118294 Hdac7-007 protein_coding Mus_musculus 0 409
ENSMUST00000116409 Hdac7-002 protein_coding Mus_musculus 0 409
ENSMUST00000119670 Hdac7-003 protein_coding Mus_musculus 0 409
ENSMUST00000121514 Hdac7-008 protein_coding Mus_musculus 0 409
ENSMUST00000088402 Hdac7-005 protein_coding Mus_musculus 0 409
ENSMUST00000116408 Hdac7-001 protein_coding Mus_musculus 0 409
ENSMUST00000079838 Hdac7-006 protein_coding Mus_musculus 0 409
ENSMUST00000145540 Hdac5-017 retained_intron Mus_musculus 0 259
ENSMUST00000155065 Hdac5-012 retained_intron Mus_musculus 0 217
ENSMUST00000134258 Hdac7-011 protein_coding Mus_musculus 1e-18 100
ENSMUST00000135651 Hdac7-012 protein_coding Mus_musculus 1e-18 100
ENSMUST00000156045 Hdac7-009 nonsense_mediated_decay Mus_musculus 1e-18 100
ENSMUST00000120683 Hdac7-004 protein_coding Mus_musculus 1e-18 100
ENSMUST00000110819 Hdac9-201 protein_coding Mus_musculus 0.000000001 71

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