C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000236959 ATIC-001 ENSG00000138363 9606 + 2:215311817-215349763 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000236959
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000236959 8.077±0.00 9.280±0.00 0.294±0.00 7.895±0.00 4.491±0.00 2.435±1.92 4.240±2.39 5.645±0.00 3.810±0.00 15.723±0.00 13.943±1.07 21.542±6.97 7.042±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MH CIL_0005MH_0001 CGP 2:214931542-215349773
CIL_0005MI CIL_0005MI_0001 CGP 2:215311817-215436172

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003360 IEA brainstem development
GO:0003824 IEA catalytic activity
GO:0003937 TAS:IEA IMP cyclohydrolase activity
GO:0004643 TAS:IEA phosphoribosylaminoimidazolecarboxamide formyltransferase activity
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006139 TAS nucleobase-containing compound metabolic process
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006189 IEA 'de novo' IMP biosynthetic process
GO:0009116 IEA nucleoside metabolic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0009259 IEA ribonucleotide metabolic process
GO:0010035 IEA response to inorganic substance
GO:0016020 IDA membrane
GO:0021549 IEA cerebellum development
GO:0021987 IEA cerebral cortex development
GO:0031100 IEA organ regeneration
GO:0042803 IPI protein homodimerization activity
GO:0044281 TAS small molecule metabolic process
GO:0046452 IEA dihydrofolate metabolic process
GO:0046654 IEA tetrahydrofolate biosynthetic process
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027384 Atic-001 protein_coding Mus_musculus 0 1888
ENSMUST00000155769 Atic-004 retained_intron Mus_musculus 0 1351
ENSMUST00000119845 Gm5721-001 processed_pseudogene Mus_musculus 0 745
ENSMUST00000154855 Atic-005 retained_intron Mus_musculus 0 429

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