C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: complement component 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000245907 C3-001 ENSG00000125730 9606 - 19:6677704-6720682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000245907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000245907 95.568±0.00 65.684±0.00 1.378±0.00 17.152±3.85 51.824±2.36 80.111±58.71 49.977±35.64 809.728±771.87 782.964±775.73 67.697±11.63 6.205±1.21 189.318±269.00 22.463±3.49 42.486±38.46

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004C9 CIL_0004C9_0001 CGP 19:6661253-6730562
CIL_00010U CIL_00010U_0001 CGP 19:6677704-6737603

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001798 IEA positive regulation of type IIa hypersensitivity
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0001970 IEA positive regulation of activation of membrane attack complex
GO:0004866 IEA endopeptidase inhibitor activity
GO:0005102 TAS receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA:IEA extracellular space
GO:0005886 TAS plasma membrane
GO:0006631 IEA fatty acid metabolic process
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0006956 IMP complement activation
GO:0006957 TAS complement activation, alternative pathway
GO:0006958 IEA complement activation, classical pathway
GO:0007165 TAS signal transduction
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0010575 IDA positive regulation vascular endothelial growth factor production
GO:0010828 IDA positive regulation of glucose transport
GO:0010866 IDA regulation of triglyceride biosynthetic process
GO:0010884 IDA positive regulation of lipid storage
GO:0010951 IEA negative regulation of endopeptidase activity
GO:0030449 TAS regulation of complement activation
GO:0031715 IDA C5L2 anaphylatoxin chemotactic receptor binding
GO:0045087 TAS innate immune response
GO:0045745 IDA positive regulation of G-protein coupled receptor protein signaling pathway
GO:0045766 IEA positive regulation of angiogenesis
GO:0050766 IEA positive regulation of phagocytosis
GO:0050776 TAS regulation of immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:2000427 IMP positive regulation of apoptotic cell clearance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000024988 C3-001 protein_coding Mus_musculus 0 3530
ENSMUST00000177046 C3-002 protein_coding Mus_musculus 0 359

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