C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: villin 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000248444 VIL1-001 ENSG00000127831 9606 + 2:218419092-218453295 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastColonLiverOvaryENST00000248444
Transcript ID Bladder Breast Colon Liver Ovary
ENST00000248444 0.409±0.00 0.906±0.00 3.366±2.66 0.397±0.00 4.256±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000650 CIL_000650_0001 CGP 2:218398256-218453295
CIL_000651 CIL_000651_0001 CGP 2:218419092-218568361

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0003779 IEA actin binding
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005902 IDA microvillus
GO:0006461 TAS protein complex assembly
GO:0007010 IEA cytoskeleton organization
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0008360 IDA regulation of cell shape
GO:0009617 IDA response to bacterium
GO:0010634 IDA positive regulation of epithelial cell migration
GO:0030027 IDA lamellipodium
GO:0030041 IDA actin filament polymerization
GO:0030042 IDA actin filament depolymerization
GO:0030175 IDA filopodium
GO:0030335 IDA positive regulation of cell migration
GO:0030855 IEP epithelial cell differentiation
GO:0032233 IDA positive regulation of actin filament bundle assembly
GO:0032432 IDA actin filament bundle
GO:0032433 ISS filopodium tip
GO:0035727 IDA lysophosphatidic acid binding
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043027 ISS cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0051014 IDA actin filament severing
GO:0051015 IDA actin filament binding
GO:0051125 IDA regulation of actin nucleation
GO:0051693 IDA actin filament capping
GO:0060327 IDA cytoplasmic actin-based contraction involved in cell motility
GO:0061041 ISS regulation of wound healing
GO:0070062 IDA extracellular vesicular exosome
GO:0071364 IDA cellular response to epidermal growth factor stimulus
GO:2000392 ISS regulation of lamellipodium morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000027366 Vil1-001 protein_coding Mus_musculus 0 2868
ENSMUST00000159749 Vil1-003 protein_coding Mus_musculus 0 688
ENSMUST00000163018 Vil1-004 retained_intron Mus_musculus 0 424
ENSMUST00000161087 Vil1-002 retained_intron Mus_musculus 0 272
ENSMUST00000044260 Usp37-002 protein_coding Mus_musculus 0 224
ENSMUST00000129173 Avil-002 protein_coding Mus_musculus 4e-39 169
ENSMUST00000026500 Avil-001 protein_coding Mus_musculus 4e-39 169

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