C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000262494 GNAO1-002 ENSG00000087258 9606 + 16:56191976-56348199 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262494
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262494 0.538±0.00 1.542±0.00 19.837±16.99 0.358±0.01 6.234±5.36 1.494±1.20 0.545±0.27 0.859±0.00 0.033±0.00 0.326±0.07 0.605±0.46 0.694±0.41 7.811±0.78

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00048R CIL_00048R_0001 CGP 16:55846154-56357444
CIL_00048U CIL_00048U_0001 CGP 16:56191390-56425538

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA:IBA GTPase activity
GO:0004871 IEA:IBA signal transducer activity
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 TAS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0006936 TAS muscle contraction
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007188 IBA adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007212 IBA dopamine receptor signaling pathway
GO:0007568 IEA aging
GO:0007626 IEA locomotory behavior
GO:0008016 IEA regulation of heart contraction
GO:0009987 IEA cellular process
GO:0010243 IEA response to organonitrogen compound
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IEA membrane
GO:0019001 IEA guanyl nucleotide binding
GO:0030900 IEA forebrain development
GO:0031175 IEA neuron projection development
GO:0031683 IEA:IBA G-protein beta/gamma-subunit complex binding
GO:0031821 IBA G-protein coupled serotonin receptor binding
GO:0031852 IBA mu-type opioid receptor binding
GO:0032403 IEA protein complex binding
GO:0032794 IEA GTPase activating protein binding
GO:0034097 IEA response to cytokine
GO:0042493 IEA response to drug
GO:0042542 IEA response to hydrogen peroxide
GO:0043005 IEA neuron projection
GO:0043234 IEA protein complex
GO:0043278 IEA response to morphine
GO:0043547 IEA positive regulation of GTPase activity
GO:0046872 IEA metal ion binding
GO:0051430 IBA corticotropin-releasing hormone receptor 1 binding
GO:0051926 IEA negative regulation of calcium ion transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000138659 Gnao1-003 processed_transcript Mus_musculus 0 1580
ENSMUST00000125716 Gnao1-002 protein_coding Mus_musculus 0 1546
ENSMUST00000034198 Gnao1-001 protein_coding Mus_musculus 0 1546
ENSDART00000150106 gnao1a-002 protein_coding Danio_rerio 0 876
ENSMUST00000137202 Gnao1-006 protein_coding Mus_musculus 0 833
ENSMUST00000125695 Gnao1-004 retained_intron Mus_musculus 0 593
ENSMUST00000055704 Gnai2-201 protein_coding Mus_musculus 0 359
ENSDART00000047528 gnai3-001 protein_coding Danio_rerio 0 311
ENSMUST00000130974 Gnao1-008 retained_intron Mus_musculus 0 248

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