C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DNA (cytosine-5-)-methyltransferase 3 alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264709 DNMT3A-001 ENSG00000119772 9606 - 2:25227855-25342590 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENST00000264709
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENST00000264709 1.026±0.00 0.818±0.00 1.955±0.00 1.318±0.00 1.312±0.00 0.355±0.00 2.282±0.00 0.350±0.00 1.030±0.00 1.005±0.00 3.875±2.52 0.972±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003JL CIL_0003JL_0002 CGP 2:25227855-25673647

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000775 IEA chromosome, centromeric region
GO:0000791 IDA euchromatin
GO:0000792 IEA heterochromatin
GO:0001741 IEA XY body
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0003886 IDA DNA (cytosine-5-)-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005720 IEA nuclear heterochromatin
GO:0005737 IDA cytoplasm
GO:0006306 IDA DNA methylation
GO:0006346 IEA methylation-dependent chromatin silencing
GO:0006349 TAS regulation of gene expression by genetic imprinting
GO:0007283 IEA spermatogenesis
GO:0008168 IEA methyltransferase activity
GO:0010424 IEA DNA methylation on cytosine within a CG sequence
GO:0016363 IDA nuclear matrix
GO:0042802 IPI identical protein binding
GO:0043045 IEA DNA methylation involved in embryo development
GO:0043046 IEA DNA methylation involved in gamete generation
GO:0044027 IEA hypermethylation of CpG island
GO:0045322 IEA unmethylated CpG binding
GO:0046498 IEA S-adenosylhomocysteine metabolic process
GO:0046499 IEA S-adenosylmethioninamine metabolic process
GO:0046872 IEA metal ion binding
GO:0051718 IEA DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates
GO:0071230 IEA cellular response to amino acid stimulus
GO:0090116 IEA C-5 methylation of cytosine

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000174817 Dnmt3a-006 protein_coding Mus_musculus 0 4115
ENSMUST00000020991 Dnmt3a-001 protein_coding Mus_musculus 0 4115
ENSMUST00000174483 Dnmt3a-004 nonsense_mediated_decay Mus_musculus 0 3035
ENSMUST00000172689 Dnmt3a-005 protein_coding Mus_musculus 0 2970
ENSMUST00000111186 Dnmt3a-201 protein_coding Mus_musculus 0 2935
ENSMUST00000172509 Dnmt3a-008 protein_coding Mus_musculus 0 1306
ENSDART00000127557 dnmt3ab-202 protein_coding Danio_rerio 0 1064
ENSDART00000005239 dnmt3ab-201 protein_coding Danio_rerio 0 1064
ENSDART00000126823 dnmt3ab-001 protein_coding Danio_rerio 0 1064
ENSDART00000151921 dnmt3ab-002 protein_coding Danio_rerio 0 1064
ENSDART00000031712 dnmt3aa-201 protein_coding Danio_rerio 0 880
ENSDART00000100320 dnmt3aa-001 protein_coding Danio_rerio 0 880
ENSMUST00000172719 Dnmt3a-017 protein_coding Mus_musculus 0 819
ENSMUST00000174774 Dnmt3a-012 protein_coding Mus_musculus 0 756
ENSMUST00000085826 Dnmt3a-003 retained_intron Mus_musculus 0 623
ENSMUST00000174733 Dnmt3a-015 nonsense_mediated_decay Mus_musculus 0 497
ENSMUST00000174102 Dnmt3a-010 protein_coding Mus_musculus 0 462
ENSMUST00000172749 Dnmt3a-013 protein_coding Mus_musculus 0 433
ENSMUST00000172913 Dnmt3a-016 protein_coding Mus_musculus 0 344
ENSMUST00000173197 Dnmt3a-009 protein_coding Mus_musculus 0 339
ENSMUST00000172879 Dnmt3a-011 protein_coding Mus_musculus 4.00001e-41 176
ENSMUST00000173700 Dnmt3a-002 retained_intron Mus_musculus 3e-34 152

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