C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: polymerase (DNA directed), gamma
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000268124 POLG-001 ENSG00000140521 9606 - 15:89316303-89334847 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainLiverLungMuscleOvaryPlacentaENST00000268124
Transcript ID Brain Liver Lung Muscle Ovary Placenta
ENST00000268124 1.546±0.57 1.898±0.34 4.175±3.03 7.148±0.00 4.850±0.64 3.621±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00011C CIL_00011C_0001 CGP 15:89209869-89317261
CIL_0002RC CIL_0002RC_0002 CGP 15:89243949-89334861
CIL_0002R9 CIL_0002R9_0002 CGP 15:89316303-89496613

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IDA:IEA DNA-directed DNA polymerase activity
GO:0004527 IEA exonuclease activity
GO:0005515 IPI protein binding
GO:0005739 TAS mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0005760 IEA gamma DNA polymerase complex
GO:0006259 TAS DNA metabolic process
GO:0006260 IEA DNA replication
GO:0006261 TAS:IEA DNA-dependent DNA replication
GO:0006264 IEA mitochondrial DNA replication
GO:0006287 IDA base-excision repair, gap-filling
GO:0007568 IEA aging
GO:0008219 IEA cell death
GO:0042645 IDA mitochondrial nucleoid
GO:0070062 IDA extracellular vesicular exosome
GO:0071897 IEA DNA biosynthetic process
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000073889 Polg-001 protein_coding Mus_musculus 0 4274
ENSMUST00000127082 Polg-003 retained_intron Mus_musculus 0 3243
ENSMUST00000149444 Polg-002 nonsense_mediated_decay Mus_musculus 0 2580
ENSMUST00000154403 Polg-004 retained_intron Mus_musculus 0 1033
ENSMUST00000145154 Polg-013 retained_intron Mus_musculus 0 726
ENSMUST00000132048 Polg-009 processed_transcript Mus_musculus 0 582
ENSMUST00000139795 Polg-012 retained_intron Mus_musculus 0 575
ENSMUST00000142915 Polg-006 retained_intron Mus_musculus 0 542
ENSMUST00000139597 Polg-010 retained_intron Mus_musculus 0 457
ENSMUST00000036865 Fanci-201 protein_coding Mus_musculus 0 302
ENSMUST00000132091 Fanci-004 nonsense_mediated_decay Mus_musculus 0 302
ENSMUST00000117227 Fanci-001 protein_coding Mus_musculus 0 302
ENSMUST00000125562 Polg-005 processed_transcript Mus_musculus 0 261
ENSMUST00000139668 Polg-008 protein_coding Mus_musculus 0 246
ENSMUST00000139290 Polg-014 processed_transcript Mus_musculus 0 246
ENSMUST00000143672 Polg-007 protein_coding Mus_musculus 2e-25 122

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