C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon regulatory factor 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000268638 IRF8-001 ENSG00000140968 9606 + 16:85898803-85922609 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268638
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268638 2.159±0.00 40.062±0.00 0.200±0.00 0.534±0.29 2.961±1.70 1.166±0.53 0.537±0.33 0.926±0.00 2.109±0.30 4.076±1.35 0.081±0.00 2.944±0.92 2.012±0.26 2.011±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000IY CIL_0000IY_0001 CGP 16:85798633-85922609
CIL_0000YG CIL_0000YG_0002 CGP 16:85898803-86515418

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000975 IEA regulatory region DNA binding
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006909 IEA phagocytosis
GO:0006955 TAS immune response
GO:0009617 IEA response to bacterium
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030099 IEA myeloid cell differentiation
GO:0032729 IEA positive regulation of interferon-gamma production
GO:0032735 IEA positive regulation of interleukin-12 production
GO:0042742 IEA defense response to bacterium
GO:0042832 IEA defense response to protozoan
GO:0044130 IEA negative regulation of growth of symbiont in host
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0060261 IEA positive regulation of transcription initiation from RNA polymerase II promoter
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047737 Irf8-001 protein_coding Mus_musculus 0 1384
ENSMUST00000162001 Irf8-003 protein_coding Mus_musculus 0 1375
ENSMUST00000160388 Irf8-006 retained_intron Mus_musculus 0 660
ENSMUST00000160594 Irf8-007 processed_transcript Mus_musculus 0 431
ENSMUST00000160943 Irf8-004 protein_coding Mus_musculus 0 351
ENSMUST00000162658 Irf8-005 protein_coding Mus_musculus 0 285

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