C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: arrestin, beta 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000269260 ARRB2-002 ENSG00000141480 9606 + 17:4710489-4721471 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartOvaryPlacentaTestisENST00000269260
Transcript ID Adipose Breast Heart Ovary Placenta Testis
ENST00000269260 5.518±0.00 3.724±0.00 0.091±0.00 9.838±5.16 5.951±0.37 3.684±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PS CIL_0001PS_0001 CGP 17:4671385-4721499
CIL_000106 CIL_000106_0001 CGP 17:4710489-4733610

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001664 IPI G-protein coupled receptor binding
GO:0002031 IDA G-protein coupled receptor internalization
GO:0002032 IMP desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002092 IMP positive regulation of receptor internalization
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005905 IEA coated pit
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0007596 TAS blood coagulation
GO:0015031 IEA protein transport
GO:0016567 IMP protein ubiquitination
GO:0019899 IPI enzyme binding
GO:0030139 IDA endocytic vesicle
GO:0030168 TAS platelet activation
GO:0031397 IDA negative regulation of protein ubiquitination
GO:0031398 IGI positive regulation of protein ubiquitination
GO:0031410 IDA cytoplasmic vesicle
GO:0031623 IDA receptor internalization
GO:0031625 IPI ubiquitin protein ligase binding
GO:0031701 IPI angiotensin receptor binding
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032947 IDA protein complex scaffold
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045953 IMP negative regulation of natural killer cell mediated cytotoxicity
GO:0060326 IMP cell chemotaxis
GO:0060765 IDA regulation of androgen receptor signaling pathway
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102564 Arrb2-007 protein_coding Mus_musculus 0 1653
ENSMUST00000102563 Arrb2-001 protein_coding Mus_musculus 0 1615
ENSMUST00000108568 Arrb2-013 protein_coding Mus_musculus 0 1496
ENSMUST00000079056 Arrb2-005 protein_coding Mus_musculus 0 1482
ENSMUST00000084954 Arrb2-006 protein_coding Mus_musculus 0 1158
ENSMUST00000128748 Arrb2-011 nonsense_mediated_decay Mus_musculus 0 1105
ENSMUST00000143232 Arrb2-002 retained_intron Mus_musculus 0 728
ENSMUST00000124943 Arrb2-009 protein_coding Mus_musculus 0 673
ENSMUST00000138006 Arrb2-012 retained_intron Mus_musculus 0 647
ENSMUST00000144454 Arrb2-003 retained_intron Mus_musculus 0 531
ENSMUST00000150076 Arrb2-010 protein_coding Mus_musculus 0 429
ENSMUST00000125441 Arrb2-004 retained_intron Mus_musculus 0 363
ENSMUST00000124112 Arrb2-008 retained_intron Mus_musculus 1.99965e-42 178

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