C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: insulin-like growth factor binding protein 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000269593 IGFBP4-001 ENSG00000141753 9606 + 17:40443461-40457731 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269593
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269593 1032.370±0.00 929.569±0.00 18.861±0.00 15.733±14.43 62.289±38.06 434.325±420.09 58.851±54.59 243.670±178.22 345.087±327.95 216.442±201.04 20.900±17.56 1237.813±1744.10 324.039±65.18 76.227±30.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005R1 CIL_0005R1_0001 CGP 17:40388516-40457731
CIL_0005R3 CIL_0005R3_0001 CGP 17:40443461-40501597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0001558 IEA regulation of cell growth
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IEA extracellular space
GO:0006259 TAS DNA metabolic process
GO:0006954 IEA inflammatory response
GO:0007165 TAS signal transduction
GO:0008283 TAS cell proliferation
GO:0010906 IEA regulation of glucose metabolic process
GO:0040008 IEA regulation of growth
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043568 IEA positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044267 TAS cellular protein metabolic process
GO:0044342 IEA type B pancreatic cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000017637 Igfbp4-001 protein_coding Mus_musculus 0 1125
ENSMUST00000130530 Igfbp4-004 processed_transcript Mus_musculus 0 523
ENSMUST00000123946 Igfbp4-003 processed_transcript Mus_musculus 0 521
ENSMUST00000140772 Igfbp4-002 protein_coding Mus_musculus 0 520
ENSMUST00000177092 Igfbp4-005 protein_coding Mus_musculus 0 235

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