C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: DIS3 like 3'-5' exoribonuclease 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000273009 DIS3L2-001 ENSG00000144535 9606 + 2:231961245-232344350 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastColonHeartKidneyLungOvaryENST00000273009
Transcript ID Adrenal Bladder Breast Colon Heart Kidney Lung Ovary
ENST00000273009 1.435±0.00 1.112±0.00 0.906±0.00 1.041±0.27 0.496±0.00 1.347±0.00 1.770±0.00 2.478±0.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000899 CIL_000899_0001 VISTA 2:231361987-231963495
CIL_0007WD CIL_0007WD_0001 VISTA 2:231362545-231967398
CIL_0007FN CIL_0007FN_0001 CGP 2:231921820-232344350
CIL_0007FQ CIL_0007FQ_0001 CGP 2:231961245-232382889

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000175 IDA 3'-5'-exoribonuclease activity
GO:0000287 IDA magnesium ion binding
GO:0000291 IMP nuclear-transcribed mRNA catabolic process, exonucleolytic
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0004540 IDA ribonuclease activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005844 TAS polysome
GO:0007067 IMP mitotic nuclear division
GO:0008266 IDA poly(U) RNA binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0010587 ISS miRNA catabolic process
GO:0019827 ISS stem cell maintenance
GO:0034427 IEA nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
GO:0051306 IMP mitotic sister chromatid separation
GO:0090501 IDA RNA phosphodiester bond hydrolysis
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1990074 ISS polyuridylation-dependent mRNA catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000065694 Dis3l2-002 protein_coding Mus_musculus 0 1836
ENSMUST00000168237 Dis3l2-001 protein_coding Mus_musculus 0 1273
ENSMUST00000190618 Dis3l2-003 nonsense_mediated_decay Mus_musculus 0 1271
ENSMUST00000189044 Dis3l2-005 retained_intron Mus_musculus 0 776
ENSMUST00000188121 Dis3l2-004 processed_transcript Mus_musculus 0 394

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