C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000278671 LAMTOR1-001 ENSG00000149357 9606 - 11:72097292-72103387 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000278671
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000278671 57.264±0.00 62.196±0.00 2.704±0.00 19.451±14.92 31.178±28.20 18.312±13.66 12.783±9.51 26.007±23.70 11.486±8.71 21.829±0.00 12.291±1.97 41.142±30.49 59.909±28.38 22.560±17.39

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XL CIL_0008XL_0001 VISTA 11:72069476-72670457
CIL_0002MI CIL_0002MI_0001 CGP 11:72080331-72110782

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001919 ISS regulation of receptor recycling
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005764 IDA lysosome
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0007032 ISS endosome organization
GO:0007040 ISS lysosome organization
GO:0010872 IMP regulation of cholesterol esterification
GO:0010874 IMP regulation of cholesterol efflux
GO:0016049 IMP cell growth
GO:0031902 ISS late endosome membrane
GO:0032008 IMP positive regulation of TOR signaling
GO:0032418 ISS lysosome localization
GO:0032439 ISS endosome localization
GO:0032947 IDA protein complex scaffold
GO:0034613 IMP cellular protein localization
GO:0042632 IMP cholesterol homeostasis
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043410 ISS positive regulation of MAPK cascade
GO:0043547 IDA positive regulation of GTPase activity
GO:0045121 ISS membrane raft
GO:0060620 IMP regulation of cholesterol import
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071986 IDA Ragulator complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033131 Lamtor1-201 protein_coding Mus_musculus 0 1221
ENSMUST00000117826 Gm5510-001 processed_pseudogene Mus_musculus 0 665
ENSMUST00000121941 Gm13077-001 processed_pseudogene Mus_musculus 0 634

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