C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: A kinase (PRKA) anchor protein 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000280979 AKAP6-001 ENSG00000151320 9606 + 14:32329273-32837681 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartOvaryTestisENST00000280979
Transcript ID Brain Heart Ovary Testis
ENST00000280979 2.493±0.98 1.798±0.33 0.058±0.00 0.334±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H7 CIL_0000H7_0001 CGP 14:32076114-32837681
CIL_0007W5 CIL_0007W5_0001 VISTA 14:32170844-32774888
CIL_0005RB CIL_0005RB_0002 CGP 14:32329273-33804176

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001508 IC action potential
GO:0005515 IPI protein binding
GO:0005635 IDA nuclear envelope
GO:0005737 ISS cytoplasm
GO:0005901 ISS caveola
GO:0006605 NAS protein targeting
GO:0008179 ISS adenylate cyclase binding
GO:0010738 ISS regulation of protein kinase A signaling
GO:0010880 IC regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0014701 ISS junctional sarcoplasmic reticulum membrane
GO:0014704 ISS intercalated disc
GO:0016529 IDA sarcoplasmic reticulum
GO:0019933 NAS cAMP-mediated signaling
GO:0030307 ISS positive regulation of cell growth
GO:0030315 ISS T-tubule
GO:0030818 ISS negative regulation of cAMP biosynthetic process
GO:0032514 ISS positive regulation of protein phosphatase type 2B activity
GO:0032947 ISS protein complex scaffold
GO:0034237 ISS protein kinase A regulatory subunit binding
GO:0034704 IDA calcium channel complex
GO:0043495 ISS protein anchor
GO:0044325 IPI ion channel binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051018 NAS protein kinase A binding
GO:0051281 ISS positive regulation of release of sequestered calcium ion into cytosol
GO:0051533 ISS positive regulation of NFAT protein import into nucleus
GO:0060306 IDA regulation of membrane repolarization
GO:0060316 ISS positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0061051 ISS positive regulation of cell growth involved in cardiac muscle cell development
GO:0070886 ISS positive regulation of calcineurin-NFAT signaling cascade
GO:0071320 IDA cellular response to cAMP
GO:0071345 ISS cellular response to cytokine stimulus
GO:1901381 IDA positive regulation of potassium ion transmembrane transport
GO:1902261 IDA positive regulation of delayed rectifier potassium channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000095737 Akap6-201 protein_coding Mus_musculus 0 7317

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