C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ATPase, Na+/K+ transporting, alpha 1 polypeptide
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000295598 ATP1A1-001 ENSG00000163399 9606 + 1:116373260-116404774 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295598
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295598 103.479±0.00 94.312±0.00 133.600±0.00 147.716±83.87 40.723±17.68 85.069±22.15 53.986±45.59 647.830±628.86 41.110±24.59 145.041±125.05 14.692±13.44 86.612±36.82 94.375±2.12 77.218±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012S CIL_00012S_0002 CGP 1:116111755-116410261

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002028 ISS regulation of sodium ion transport
GO:0005391 ISS:IEA sodium:potassium-exchanging ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 ISS endoplasmic reticulum
GO:0005794 ISS Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005890 IDA sodium:potassium-exchanging ATPase complex
GO:0006754 IEA ATP biosynthetic process
GO:0006813 IEA potassium ion transport
GO:0006814 IEA sodium ion transport
GO:0006883 IDA cellular sodium ion homeostasis
GO:0010107 IDA potassium ion import
GO:0016020 TAS membrane
GO:0016021 ISS:IEA integral component of membrane
GO:0030007 IDA cellular potassium ion homeostasis
GO:0031982 IDA vesicle
GO:0034220 TAS ion transmembrane transport
GO:0036376 IDA sodium ion export from cell
GO:0042383 ISS sarcolemma
GO:0043234 IDA protein complex
GO:0046872 IEA metal ion binding
GO:0051087 IPI chaperone binding
GO:0055085 TAS transmembrane transport
GO:0055119 TAS relaxation of cardiac muscle
GO:0060048 TAS cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0071383 IDA cellular response to steroid hormone stimulus
GO:0086009 IDA membrane repolarization
GO:0086013 IC membrane repolarization during cardiac muscle cell action potential
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction
GO:1903416 IDA response to glycoside
GO:1990239 IDA steroid hormone binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000036493 Atp1a1-001 protein_coding Mus_musculus 0 4338
ENSMUST00000080882 Atp1a3-001 protein_coding Mus_musculus 0 1958
ENSMUST00000102858 Atp1a3-002 protein_coding Mus_musculus 0 1940
ENSDART00000006449 atp1a1a.2-001 protein_coding Danio_rerio 0 1240
ENSMUST00000136340 Atp1a1-002 retained_intron Mus_musculus 0 424
ENSMUST00000130649 Atp1a1-003 retained_intron Mus_musculus 0 359

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