C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, AMPA 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000296526 GRIA2-001 ENSG00000120251 9606 + 4:157220718-157366075 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainMuscleOvaryTestisENST00000296526
Transcript ID Brain Muscle Ovary Testis
ENST00000296526 10.539±4.43 0.089±0.00 0.091±0.00 0.079±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006DX CIL_0006DX_0002 CGP 4:157076057-157366075
CIL_00007X CIL_00007X_0002 CGP 4:157204182-158173318

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004970 IDA:IEA ionotropic glutamate receptor activity
GO:0004971 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:0005234 IBA:IEA extracellular-glutamate-gated ion channel activity
GO:0005515 IPI protein binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007165 TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0008021 IEA synaptic vesicle
GO:0016020 IEA membrane
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0030666 TAS endocytic vesicle membrane
GO:0032281 ISS alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0034220 IEA ion transmembrane transport
GO:0035235 IDA ionotropic glutamate receptor signaling pathway
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0045202 IEA synapse
GO:0045211 IBA postsynaptic membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000107745 Gria2-202 protein_coding Mus_musculus 0 5288
ENSMUST00000075316 Gria2-201 protein_coding Mus_musculus 0 5110
ENSDART00000064617 gria2b-001 protein_coding Danio_rerio 0 1916
ENSDART00000074671 gria2b-002 protein_coding Danio_rerio 0 1415
ENSMUST00000063508 Gria4-202 protein_coding Mus_musculus 0 1048
ENSMUST00000076349 Gria3-001 protein_coding Mus_musculus 0 1029
ENSMUST00000151045 Gria1-006 protein_coding Mus_musculus 0 859
ENSMUST00000036315 Gria1-004 protein_coding Mus_musculus 0 859
ENSDART00000123713 gria1b-003 protein_coding Danio_rerio 0 592
ENSDART00000134602 gria2b-003 processed_transcript Danio_rerio 0 490
ENSDART00000077805 gria2a-002 protein_coding Danio_rerio 0 477
ENSMUST00000139965 Gria3-002 nonsense_mediated_decay Mus_musculus 0 289

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