C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: AXL receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000301178 AXL-001 ENSG00000167601 9606 + 19:41219203-41261766 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000301178
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000301178 37.281±0.00 9.241±0.00 6.176±0.00 9.505±6.55 20.898±0.00 3.677±0.00 5.714±0.00 11.735±0.00 2.687±2.28 6.284±2.94 12.972±2.26 11.423±4.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TR CIL_0008TR_0001 VISTA 19:41131081-41732986

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0001779 IEA natural killer cell differentiation
GO:0001786 IDA phosphatidylserine binding
GO:0001961 IDA positive regulation of cytokine-mediated signaling pathway
GO:0001974 IEA blood vessel remodeling
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0006909 IDA phagocytosis
GO:0006954 IEA inflammatory response
GO:0007165 TAS signal transduction
GO:0007167 IEA enzyme linked receptor protein signaling pathway
GO:0007283 IEA spermatogenesis
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021885 IEA forebrain cell migration
GO:0030154 IEA cell differentiation
GO:0030168 IEA platelet activation
GO:0031100 IEA organ regeneration
GO:0031668 IEA cellular response to extracellular stimulus
GO:0032036 IEA myosin heavy chain binding
GO:0032689 IDA negative regulation of interferon-gamma production
GO:0032720 IEA negative regulation of tumor necrosis factor production
GO:0032825 IDA positive regulation of natural killer cell differentiation
GO:0032940 IEA secretion by cell
GO:0034101 IEA erythrocyte homeostasis
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0035457 IDA cellular response to interferon-alpha
GO:0042698 IEA ovulation cycle
GO:0043066 IEA negative regulation of apoptotic process
GO:0043277 IEA apoptotic cell clearance
GO:0043491 IEA protein kinase B signaling
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0045087 IEA innate immune response
GO:0046982 IEA protein heterodimerization activity
GO:0048469 IEP cell maturation
GO:0051250 IEA negative regulation of lymphocyte activation
GO:0051897 IEA positive regulation of protein kinase B signaling
GO:0060068 IEA vagina development
GO:0070062 IDA extracellular vesicular exosome
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0097028 IEP dendritic cell differentiation
GO:2000669 IDA negative regulation of dendritic cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002677 Axl-001 protein_coding Mus_musculus 0 2988
ENSMUST00000085948 Axl-002 protein_coding Mus_musculus 0 2826
ENSMUST00000132989 Axl-003 retained_intron Mus_musculus 0 1694
ENSMUST00000124442 Axl-008 retained_intron Mus_musculus 0 706
ENSMUST00000137211 Axl-007 retained_intron Mus_musculus 0 551
ENSMUST00000132038 Axl-009 protein_coding Mus_musculus 0 459
ENSMUST00000077549 Prss43-201 protein_coding Mus_musculus 0.00000000002 77

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