C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: hyperpolarization activated cyclic nucleotide-gated potassium channel 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000303230 HCN1-001 ENSG00000164588 9606 - 5:45259247-45696151 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000303230
Transcript ID Adipose Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000303230 0.105±0.00 7.962±0.37 0.060±0.00 0.036±0.03 0.032±0.01 0.006±0.00 0.054±0.00 0.143±0.11 0.008±0.01 0.007±0.00 0.045±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005222 ISS intracellular cAMP activated cation channel activity
GO:0005248 IMP voltage-gated sodium channel activity
GO:0005249 ISS voltage-gated potassium channel activity
GO:0005267 NAS potassium channel activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006813 NAS potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030552 ISS cAMP binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IMP sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0045176 IEA apical protein localization
GO:0046549 IEA retinal cone cell development
GO:0055085 IEA transmembrane transport
GO:0071320 ISS cellular response to cAMP
GO:0071805 ISS potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000006991 Hcn1-001 protein_coding Mus_musculus 0 2761
ENSDART00000136390 hcn2b-001 protein_coding Danio_rerio 0 920
ENSMUST00000020581 Hcn2-201 protein_coding Mus_musculus 0.000008 58
ENSMUST00000099513 Hcn2-001 protein_coding Mus_musculus 0.000008 58

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