C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306270 IBTK-001 ENSG00000005700 9606 - 6:82169983-82247754 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306270
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306270 1.789±0.00 1.744±0.00 0.342±0.00 4.206±0.00 2.766±1.47 2.102±0.68 1.440±0.00 1.092±0.00 2.977±0.97 1.255±0.00 4.206±1.73 1.958±0.32 1.093±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006G7 CIL_0006G7_0001 CGP 6:81491439-82247754
CIL_0006GF CIL_0006GF_0001 CGP 6:82169983-82370828

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001933 IDA negative regulation of protein phosphorylation
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0016020 IEA membrane
GO:0019901 IDA protein kinase binding
GO:0030292 IDA protein tyrosine kinase inhibitor activity
GO:0051209 IDA release of sequestered calcium ion into cytosol
GO:0061099 IDA negative regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000039213 Ibtk-001 protein_coding Mus_musculus 0 4542
ENSMUST00000185353 Ibtk-005 retained_intron Mus_musculus 0 2760
ENSMUST00000187521 Ibtk-003 nonsense_mediated_decay Mus_musculus 0 2313
ENSMUST00000186322 Ibtk-002 retained_intron Mus_musculus 0 1312
ENSMUST00000188768 Ibtk-007 retained_intron Mus_musculus 0 691
ENSMUST00000186447 Ibtk-006 retained_intron Mus_musculus 0 342
ENSMUST00000120545 Gm12178-001 processed_pseudogene Mus_musculus 0 196

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