C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Sp3 transcription factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000310015 SP3-001 ENSG00000172845 9606 - 2:173906459-173965702 protein_coding

Homo sapiens EnsemblGRCh38

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Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000310015
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000310015 2.809±0.00 3.784±0.00 0.824±0.00 0.874±0.17 2.134±0.46 0.813±0.00 0.893±0.00 1.318±0.74 2.001±0.90 1.745±0.16 0.942±0.23 0.904±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007OE CIL_0007OE_0001 UCNEbase 2:173198009-174351945
CIL_0004JD CIL_0004JD_0001 CGP 2:173354820-173965702
CIL_0008JW CIL_0008JW_0001 VISTA 2:173820816-174422736
CIL_0008K1 CIL_0008K1_0001 VISTA 2:173824009-174425635
CIL_0008S8 CIL_0008S8_0001 VISTA 2:173876675-174477772
CIL_0003II CIL_0003II_0002 CGP 2:173906459-174248698

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000987 IEA core promoter proximal region sequence-specific DNA binding
GO:0001078 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001503 IEA ossification
GO:0001701 IEA in utero embryonic development
GO:0001779 IEA natural killer cell differentiation
GO:0001829 IEA trophectodermal cell differentiation
GO:0001889 IEA liver development
GO:0001892 IEA embryonic placenta development
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003690 IEA double-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0017053 IEA transcriptional repressor complex
GO:0030183 IEA B cell differentiation
GO:0030217 IEA T cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0030219 IEA megakaryocyte differentiation
GO:0030224 IEA monocyte differentiation
GO:0030324 IEA lung development
GO:0030851 IEA granulocyte differentiation
GO:0043353 IEA enucleate erythrocyte differentiation
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046872 IEA metal ion binding
GO:0048596 IEA embryonic camera-type eye morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0060136 IEA embryonic process involved in female pregnancy
GO:0060216 IEA definitive hemopoiesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000102689 Sp3-001 protein_coding Mus_musculus 0 5973
ENSMUST00000133615 Sp3-003 processed_transcript Mus_musculus 0 5409
ENSMUST00000066003 Sp3-002 protein_coding Mus_musculus 0 5238
ENSMUST00000141372 Sp3-004 processed_transcript Mus_musculus 0 774
ENSMUST00000129565 Sp3-005 processed_transcript Mus_musculus 0 481

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