C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ubiquitin-conjugating enzyme E2N
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000318066 UBE2N-001 ENSG00000177889 9606 - 12:93405690-93442262 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonKidneyLungOvaryTestisENST00000318066
Transcript ID Adrenal Brain Colon Kidney Lung Ovary Testis
ENST00000318066 9.197±0.00 8.424±0.17 3.781±0.00 10.782±0.00 3.228±0.48 5.630±0.00 8.135±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XV CIL_0000XV_0002 CGP 12:93377883-93442262
CIL_0005X9 CIL_0005X9_0002 CGP 12:93405673-93516213

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000729 IMP DNA double-strand break processing
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006282 TAS regulation of DNA repair
GO:0006301 IMP postreplication repair
GO:0006464 TAS cellular protein modification process
GO:0006508 TAS proteolysis
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0016567 TAS protein ubiquitination
GO:0016574 IMP histone ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031058 IMP positive regulation of histone modification
GO:0031372 IDA UBC13-MMS2 complex
GO:0033182 IMP regulation of histone ubiquitination
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035370 IDA UBC13-UEV1A complex
GO:0035872 TAS nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 IDA ubiquitin binding
GO:0043234 IDA protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0045087 TAS innate immune response
GO:0045739 IMP positive regulation of DNA repair
GO:0050852 IMP T cell receptor signaling pathway
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051443 IMP positive regulation of ubiquitin-protein transferase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070423 TAS nucleotide-binding oligomerization domain containing signaling pathway
GO:0070534 IDA protein K63-linked ubiquitination

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000099329 Ube2n-201 protein_coding Mus_musculus 0 1661
ENSMUST00000119458 Gm5943-001 processed_pseudogene Mus_musculus 0 737
ENSMUST00000085228 Ube2nl-201 processed_pseudogene Mus_musculus 0 710

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