C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phospholipase A2, group VI (cytosolic, calcium-independent)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000332509 PLA2G6-001 ENSG00000184381 9606 - 22:38111495-38181802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonKidneyTestisENST00000332509
Transcript ID Adipose Brain Breast Colon Kidney Testis
ENST00000332509 1.540±0.00 2.361±1.49 1.095±0.87 0.649±0.00 0.137±0.00 10.083±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099H CIL_00099H_0001 VISTA 22:37683926-38284300
CIL_0008KJ CIL_0008KJ_0001 VISTA 22:37685616-38286450
CIL_0008BX CIL_0008BX_0001 VISTA 22:37696030-38296592
CIL_0008KA CIL_0008KA_0001 VISTA 22:37698338-38299192
CIL_00082J CIL_00082J_0001 VISTA 22:37733233-38334508
CIL_0008C1 CIL_0008C1_0001 VISTA 22:37746133-38346872
CIL_00082K CIL_00082K_0001 VISTA 22:37750385-38350990
CIL_0008MM CIL_0008MM_0001 VISTA 22:37872841-38473542
CIL_0007CL CIL_0007CL_0001 CGP 22:38084889-38205690
CIL_0003QB CIL_0003QB_0001 CGP 22:38111495-38216511

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0004623 TAS phospholipase A2 activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006629 IEA lipid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0006935 IEA chemotaxis
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007613 IEA memory
GO:0008152 IEA metabolic process
GO:0008219 IEA cell death
GO:0014832 IEA urinary bladder smooth muscle contraction
GO:0016020 IEA membrane
GO:0016042 IEA lipid catabolic process
GO:0032049 IMP cardiolipin biosynthetic process
GO:0034976 IEA response to endoplasmic reticulum stress
GO:0035774 IEA positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0035965 TAS cardiolipin acyl-chain remodeling
GO:0036151 TAS phosphatidylcholine acyl-chain remodeling
GO:0036152 TAS phosphatidylethanolamine acyl-chain remodeling
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043008 IEA ATP-dependent protein binding
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0045909 IEA positive regulation of vasodilation
GO:0045921 IEA positive regulation of exocytosis
GO:0046474 TAS glycerophospholipid biosynthetic process
GO:0047499 IEA calcium-independent phospholipase A2 activity
GO:0051967 IEA negative regulation of synaptic transmission, glutamatergic
GO:0060135 IEA maternal process involved in female pregnancy
GO:0090037 IEA positive regulation of protein kinase C signaling
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0090238 IEA positive regulation of arachidonic acid secretion
GO:1901339 IEA regulation of store-operated calcium channel activity
GO:2000304 IEA positive regulation of ceramide biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000174021 Pla2g6-005 protein_coding Mus_musculus 0 2750
ENSMUST00000172403 Pla2g6-001 protein_coding Mus_musculus 0 1360
ENSMUST00000047816 Pla2g6-003 protein_coding Mus_musculus 0 1360
ENSMUST00000173163 Pla2g6-004 protein_coding Mus_musculus 0 1360
ENSMUST00000166977 Pla2g6-002 protein_coding Mus_musculus 0 1360
ENSMUST00000174375 Pla2g6-009 retained_intron Mus_musculus 0 776

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